Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L41_RS07625 Genome accession   NZ_CP016655
Coordinates   1483401..1486427 (+) Length   1008 a.a.
NCBI ID   WP_335582221.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22772     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1478401..1491427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L41_RS07595 (A6L41_07595) hpaC 1478992..1479492 (-) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6L41_RS07600 (A6L41_07600) nadR 1479607..1480047 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L41_RS07610 (A6L41_07610) - 1480390..1480899 (-) 510 WP_002225670.1 protein disulfide oxidoreductase -
  A6L41_RS07620 (A6L41_07620) apbC 1481264..1482343 (+) 1080 WP_002248347.1 iron-sulfur cluster carrier protein ApbC -
  A6L41_RS14620 pilC 1483282..1483407 (+) 126 WP_335582220.1 hypothetical protein Machinery gene
  A6L41_RS07625 (A6L41_07625) pilC 1483401..1486427 (+) 3027 WP_335582221.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L41_RS07635 (A6L41_07635) carA 1488408..1489541 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L41_RS07640 (A6L41_07640) - 1489587..1489724 (+) 138 WP_002214606.1 VOC family protein -
  A6L41_RS07655 (A6L41_07655) - 1490304..1490693 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L41_RS13675 - 1490697..1490864 (+) 168 WP_153312129.1 hypothetical protein -

Sequence

Protein


Download         Length: 1008 a.a.        Molecular weight: 111067.45 Da        Isoelectric Point: 9.6218

>NTDB_id=190464 A6L41_RS07625 WP_335582221.1 1483401..1486427(+) (pilC) [Neisseria meningitidis strain M22772]
MVMNNQKLPEVKWGQQYQSLVNKENTRQVIHTSGFGIKKNVSLSFNNTDEVVAKKNGTVVFGAATYLPPYGKVSGFDEEK
LKERTNALDWIGTTDPGLVGYSYEDVTCNSGNCPEVSYKTQFIFDNHQLAKKKTDSKLDIYEDKSRDNSPIYKLQDYPWL
GVSFNLGGESSFKPKRQGSLVSSFSEDVTQQNGTQDQYKGKNLVYTTEDYNNQGNRNHQDKHHAIAFYLNAKLHLLDKKQ
IQNIAQGKTFNLGTLKPRIDLTEAWKNRHGSFFSNGNWTFEDKGAVSVKLILPEVKAGRCINKPNPKAQALSPALTAPAL
WFGPVQNGKVQMYSASVSTYPDSSSSRIFLQNLERKTDPGRPGRYSLETLTENDIKSRQPNFTGRQTIIRLDSGVQQIKL
QGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKEENNGKPKYSQRYRIRENGNNGNN
GKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIQNTESTLAKELRAFAEKSYVGD
RYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKHDNNGKNSNNSVQLGYTVGTPQIG
KTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMY
RFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDIQHVYGIFDNDTDTGTAQDGQGKG
LLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKYKDNGCGAETAILGINTADGGKLT
KKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGID
PAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3027 bp        

>NTDB_id=190464 A6L41_RS07625 WP_335582221.1 1483401..1486427(+) (pilC) [Neisseria meningitidis strain M22772]
ATTGTAATGAACAATCAAAAGCTGCCTGAGGTAAAGTGGGGGCAACAATATCAATCATTGGTGAACAAAGAAAATACCCG
TCAAGTTATCCATACGAGTGGTTTTGGAATCAAAAAAAACGTAAGTTTATCATTCAATAATACCGATGAAGTTGTTGCTA
AAAAAAACGGTACTGTCGTTTTCGGCGCGGCGACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATGAAGAAAAG
CTGAAAGAGCGCACCAATGCCCTTGATTGGATTGGTACGACCGACCCAGGGTTGGTAGGCTACAGCTACGAAGATGTTAC
ATGCAACAGCGGCAACTGTCCTGAAGTTAGCTATAAAACCCAATTTATCTTCGATAATCACCAGTTGGCAAAAAAGAAAA
CAGACAGCAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTCGCCCATTTACAAATTGCAGGATTATCCTTGGTTG
GGCGTGTCTTTCAATTTGGGCGGAGAGAGCTCCTTCAAACCAAAGAGACAAGGTTCTTTGGTATCTTCTTTTAGCGAGGA
TGTGACGCAGCAAAATGGTACACAAGACCAATACAAAGGCAAAAACCTCGTTTATACGACAGAAGATTACAATAATCAGG
GTAATCGTAACCATCAGGACAAACACCACGCCATCGCCTTTTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAACAA
ATCCAAAATATCGCGCAAGGCAAAACATTTAATTTGGGTACGTTGAAACCGCGCATCGATTTGACGGAAGCGTGGAAAAA
CAGGCATGGGAGCTTTTTTAGTAATGGTAATTGGACGTTTGAAGATAAAGGAGCAGTCAGCGTCAAACTTATCTTGCCGG
AAGTCAAAGCAGGCCGCTGCATCAACAAACCGAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTG
TGGTTCGGACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCG
CATCTTCCTTCAAAATCTGGAAAGAAAAACCGACCCCGGCAGACCCGGCCGCTATTCCCTCGAAACCTTGACTGAGAACG
ATATTAAAAGTCGACAGCCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTT
CAAGGCAATGAGGTCGCCAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCAC
GCCTGATGCCAATGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAG
TCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAAC
GGCAAGCGTGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGG
GATGGTGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGC
CGCGCAAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGAC
CGCTACGGCGTGGACGGCGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGAT
GGGTTTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTG
ATGTCAAACATGACAATAATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGC
AAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAAC
CGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTT
CGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTAC
CGCTTTGATTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGC
GCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACA
ACAAAGACATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGG
CTGCTCGAGCAAGTGCTTAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAA
GGGGTGGATGGTGAAATTGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCA
TCCGCAAATATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACC
AAGAAAAGCGCGCGCCCGATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGG
CAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTA
ATGTGCGCTACCTGGACGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGAC
CCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGA
CAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(485-816)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.07

100

0.732

Multiple sequence alignment