Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CAC01_RS25635 Genome accession   NZ_CP021118
Coordinates   6018811..6019491 (+) Length   226 a.a.
NCBI ID   WP_007828730.1    Uniprot ID   A0ABU2R6N2
Organism   Streptomyces sp. CLI2509 strain CLI2905     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6013811..6024491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAC01_RS25625 (CAC01_25545) - 6016284..6017150 (-) 867 WP_043256459.1 transglycosylase SLT domain-containing protein -
  CAC01_RS25630 (CAC01_25550) - 6017604..6018746 (+) 1143 WP_043257789.1 GAF domain-containing sensor histidine kinase -
  CAC01_RS25635 (CAC01_25555) vraR 6018811..6019491 (+) 681 WP_007828730.1 response regulator transcription factor Regulator
  CAC01_RS33165 (CAC01_25560) - 6019652..6019996 (+) 345 WP_007828731.1 chaplin -
  CAC01_RS25645 (CAC01_25565) - 6020142..6020381 (+) 240 WP_007828732.1 chaplin -
  CAC01_RS25650 (CAC01_25570) - 6020493..6021277 (-) 785 Protein_5032 hypothetical protein -
  CAC01_RS25655 (CAC01_25575) - 6021414..6022205 (+) 792 WP_009063948.1 ABC transporter ATP-binding protein -
  CAC01_RS25660 (CAC01_25580) - 6022305..6022736 (+) 432 WP_009063946.1 NfeD family protein -
  CAC01_RS25665 (CAC01_25585) - 6022923..6023906 (+) 984 WP_007828735.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24327.76 Da        Isoelectric Point: 5.1798

>NTDB_id=190459 CAC01_RS25635 WP_007828730.1 6018811..6019491(+) (vraR) [Streptomyces sp. CLI2509 strain CLI2905]
MPAEEGKAGAAPGGPRPIRVLIVDDHQVVRRGLRTFLEIQDDIEVVGEAADGDEGVARAGELRPDVILMDVKMPGTDGVE
ALRTLRALGNEVRVLIVTSFTEQRTVVPALRAGAAGYVYKDIDPEALAGAIRSVHAGHVLLQPEVAGMLLAQEEQAPQQP
RGGSLTEREREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGYSD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=190459 CAC01_RS25635 WP_007828730.1 6018811..6019491(+) (vraR) [Streptomyces sp. CLI2509 strain CLI2905]
GTGCCCGCGGAAGAGGGGAAGGCGGGCGCCGCGCCCGGCGGCCCCCGCCCGATCCGGGTGCTCATCGTCGACGACCACCA
GGTCGTCCGCCGGGGCCTGCGCACCTTCCTGGAGATCCAGGACGACATCGAGGTGGTCGGCGAGGCCGCGGACGGCGACG
AAGGCGTCGCGCGCGCGGGCGAGCTGCGCCCCGACGTGATCCTCATGGACGTGAAGATGCCCGGCACCGACGGCGTCGAG
GCACTGCGCACCCTGCGGGCCCTCGGCAACGAGGTACGGGTCCTGATCGTGACGAGCTTCACCGAGCAGCGCACCGTGGT
GCCCGCGCTGCGCGCCGGAGCGGCCGGCTACGTGTACAAGGACATCGACCCCGAGGCCCTCGCCGGGGCGATCCGCTCCG
TGCACGCCGGGCACGTCCTCCTCCAGCCGGAGGTCGCGGGGATGCTCCTCGCCCAGGAGGAGCAGGCCCCGCAGCAGCCG
CGCGGCGGCTCCCTCACGGAACGCGAGCGCGAGGTGCTCGGCCTCATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCG
CGCGCTCGTCCTCTCCGAGAAGACGGTGAAGACGCACGTGTCGAACATCCTCATGAAACTCGACCTCGCCGACCGCACCC
AGGCCGCCCTGTGGGCCGTACGGCACGGCTACAGCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(20-131)

Bacterial regulatory proteins, luxR family (GerE)

(164-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.894

91.593

0.42
  degU Bacillus subtilis subsp. subtilis str. 168

39.64

98.23

0.389