Detailed information
Bioinformatically predicted
Overview
| Name | comE | Type | Machinery gene |
| Locus tag | A6L48_RS14775 | Genome accession | NZ_CP016654 |
| Coordinates | 115221..115685 (-) | Length | 154 a.a. |
| NCBI ID | WP_164742033.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain M22811 | ||
| Function | DNA binding (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 89776..121866 | 115221..115685 | within | 0 |
Gene organization within MGE regions
Location: 89776..121866
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A6L48_RS00545 (A6L48_00545) | - | 90114..90767 (-) | 654 | Protein_101 | UTP--glucose-1-phosphate uridylyltransferase | - |
| A6L48_RS00550 (A6L48_00550) | - | 90815..91984 (-) | 1170 | WP_019273883.1 | DUF6716 putative glycosyltransferase | - |
| A6L48_RS00555 (A6L48_00555) | - | 92034..92711 (-) | 678 | WP_002215827.1 | IS1595-like element ISNme3 family transposase | - |
| A6L48_RS11465 | - | 92762..93148 (-) | 387 | WP_002228841.1 | acyltransferase | - |
| A6L48_RS00570 (A6L48_00570) | - | 94323..97436 (-) | 3114 | WP_002239419.1 | glycosyltransferase | - |
| A6L48_RS00575 (A6L48_00575) | siaC | 97588..98637 (-) | 1050 | WP_002228845.1 | polysialic acid capsule biosynthesis protein SiaC | - |
| A6L48_RS00580 (A6L48_00580) | neuA | 98638..99324 (-) | 687 | WP_002215295.1 | N-acylneuraminate cytidylyltransferase | - |
| A6L48_RS00585 (A6L48_00585) | neuC | 99328..100461 (-) | 1134 | WP_002224373.1 | UDP-N-acetylglucosamine 2-epimerase | - |
| A6L48_RS00590 (A6L48_00590) | ctrA | 100596..101771 (+) | 1176 | WP_002215290.1 | capsule polysaccharide export outer membrane protein CtrA | - |
| A6L48_RS00595 (A6L48_00595) | ctrB | 101786..102949 (+) | 1164 | WP_002215287.1 | capsule polysaccharide export protein CtrB | - |
| A6L48_RS00600 (A6L48_00600) | - | 102949..103746 (+) | 798 | WP_002218515.1 | ABC transporter permease | - |
| A6L48_RS00605 (A6L48_00605) | - | 103743..104393 (+) | 651 | WP_002215285.1 | ABC transporter ATP-binding protein | - |
| A6L48_RS00610 (A6L48_00610) | - | 104458..106731 (+) | 2274 | WP_002230176.1 | Tex family protein | - |
| A6L48_RS00615 (A6L48_00615) | - | 106762..107592 (+) | 831 | WP_002215283.1 | DNA cytosine methyltransferase | - |
| A6L48_RS15590 | - | 107570..107764 (+) | 195 | WP_002215282.1 | DNA cytosine methyltransferase | - |
| A6L48_RS00620 (A6L48_00620) | - | 107757..108101 (+) | 345 | WP_002231447.1 | DNA adenine methylase | - |
| A6L48_RS00625 (A6L48_00625) | galE | 108180..108800 (+) | 621 | Protein_118 | UDP-glucose 4-epimerase GalE | - |
| A6L48_RS00630 (A6L48_00630) | rfbB | 108801..109883 (+) | 1083 | WP_002258424.1 | dTDP-glucose 4,6-dehydratase | - |
| A6L48_RS00635 (A6L48_00635) | rfbA | 110080..110970 (+) | 891 | WP_002258018.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| A6L48_RS00640 (A6L48_00640) | rfbC | 111015..111572 (+) | 558 | WP_002234441.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
| A6L48_RS00645 (A6L48_00645) | - | 111616..113634 (-) | 2019 | WP_002216177.1 | OPT family oligopeptide transporter | - |
| A6L48_RS00650 (A6L48_00650) | dnaJ | 113830..114951 (-) | 1122 | WP_002235332.1 | molecular chaperone DnaJ | - |
| A6L48_RS14775 | comE | 115221..115685 (-) | 465 | WP_164742033.1 | ComEA family DNA-binding protein | Machinery gene |
| A6L48_RS00700 (A6L48_00700) | dksA | 121450..121866 (-) | 417 | WP_002231430.1 | RNA polymerase-binding protein DksA | - |
Sequence
Protein
Download Length: 154 a.a. Molecular weight: 16514.78 Da Isoelectric Point: 10.6993
>NTDB_id=190431 A6L48_RS14775 WP_164742033.1 115221..115685(-) (comE) [Neisseria meningitidis strain M22811]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
Nucleotide
Download Length: 465 bp
>NTDB_id=190431 A6L48_RS14775 WP_164742033.1 115221..115685(-) (comE) [Neisseria meningitidis strain M22811]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTGAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTGAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |