Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   A6L48_RS10815 Genome accession   NZ_CP016654
Coordinates   2060765..2061460 (-) Length   231 a.a.
NCBI ID   WP_002234519.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22811     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2034629..2062290 2060765..2061460 within 0


Gene organization within MGE regions


Location: 2034629..2062290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L48_RS10670 (A6L48_10670) - 2034629..2034988 (-) 360 WP_002221979.1 immunity 8 family protein -
  A6L48_RS10675 (A6L48_10675) queF 2035252..2035725 (+) 474 WP_002234526.1 preQ(1) synthase -
  A6L48_RS10680 (A6L48_10680) - 2035800..2036486 (+) 687 WP_002212282.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
  A6L48_RS15940 - 2036778..2036989 (+) 212 Protein_1974 hypothetical protein -
  A6L48_RS10685 (A6L48_10685) - 2037425..2038717 (-) 1293 WP_002220262.1 M23 family metallopeptidase -
  A6L48_RS10690 (A6L48_10690) - 2038795..2039763 (+) 969 WP_002251034.1 hypothetical protein -
  A6L48_RS10695 (A6L48_10695) - 2039964..2041427 (-) 1464 WP_002216379.1 surface lipoprotein assembly modifier -
  A6L48_RS10700 (A6L48_10700) autA 2041669..2043054 (-) 1386 Protein_1978 autoaggregation autotransporter AutA -
  A6L48_RS10705 (A6L48_10705) - 2043102..2043779 (+) 678 WP_002215827.1 IS1595-like element ISNme3 family transposase -
  A6L48_RS10710 (A6L48_10710) - 2043792..2044280 (-) 489 WP_002258458.1 hypothetical protein -
  A6L48_RS10715 (A6L48_10715) - 2045926..2046171 (-) 246 WP_002212272.1 hypothetical protein -
  A6L48_RS10725 (A6L48_10725) - 2046283..2046711 (+) 429 WP_002212270.1 CopD family protein -
  A6L48_RS10730 (A6L48_10730) - 2046723..2047199 (+) 477 WP_002231682.1 CYTH domain-containing protein -
  A6L48_RS10735 (A6L48_10735) - 2047549..2048037 (-) 489 WP_002218701.1 dihydrofolate reductase -
  A6L48_RS10740 (A6L48_10740) aroG 2048105..2049160 (-) 1056 WP_002212267.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  A6L48_RS15185 - 2049322..2049549 (-) 228 WP_153310284.1 hypothetical protein -
  A6L48_RS10750 (A6L48_10750) - 2049827..2050084 (+) 258 WP_002231679.1 membrane protein -
  A6L48_RS10755 (A6L48_10755) - 2050066..2050275 (-) 210 Protein_1988 transposase -
  A6L48_RS10760 (A6L48_10760) - 2050440..2051093 (-) 654 WP_019742811.1 IS1595 family transposase -
  A6L48_RS15560 - 2051213..2051671 (-) 459 WP_002234522.1 hypothetical protein -
  A6L48_RS15195 (A6L48_10770) comE 2051783..2052247 (-) 465 WP_164993478.1 ComEA family DNA-binding protein Machinery gene
  A6L48_RS10805 (A6L48_10805) - 2058038..2058844 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L48_RS10810 (A6L48_10810) ffh 2059064..2060434 (+) 1371 WP_002258651.1 signal recognition particle protein -
  A6L48_RS10815 (A6L48_10815) dsbA2 2060765..2061460 (-) 696 WP_002234519.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L48_RS10820 (A6L48_10820) - 2061631..2062290 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25447.95 Da        Isoelectric Point: 5.1502

>NTDB_id=190429 A6L48_RS10815 WP_002234519.1 2060765..2061460(-) (dsbA2) [Neisseria meningitidis strain M22811]
MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=190429 A6L48_RS10815 WP_002234519.1 2060765..2061460(-) (dsbA2) [Neisseria meningitidis strain M22811]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGCGT
TCCGGCAGACAGCGTCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

99.567

100

0.996
  dsbA1 Neisseria meningitidis MC58

70.815

100

0.714

Multiple sequence alignment