Detailed information NTG0190427

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6L48_RS10595
• Genome accession: NZ_CP016654
• Coordinates: 2023146..2024006 (+)
• Length: 286 a.a.
• NCBI ID: WP_002223365.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22811
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2018146..2029006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L48_RS10580 (A6L48_10580)	dapD	2018656..2019477 (-)	822	WP_002212339.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
A6L48_RS13325	-	2019487..2019717 (-)	231	WP_025462714.1	hypothetical protein	-
A6L48_RS10585 (A6L48_10585)	pgi	2019687..2021330 (-)	1644	WP_002220279.1	glucose-6-phosphate isomerase	-
A6L48_RS10590 (A6L48_10590)	pilG	2021840..2023072 (+)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
A6L48_RS10595 (A6L48_10595)	pilD	2023146..2024006 (+)	861	WP_002223365.1	prepilin peptidase	Machinery gene
A6L48_RS10600 (A6L48_10600)	coaE	2024008..2024640 (+)	633	WP_002258461.1	dephospho-CoA kinase	-
A6L48_RS10605 (A6L48_10605)	-	2024633..2024842 (+)	210	WP_002226982.1	DNA gyrase inhibitor YacG	-
A6L48_RS10610 (A6L48_10610)	pilF	2024927..2026603 (-)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6L48_RS10620 (A6L48_10620)	-	2027095..2027541 (-)	447	WP_002220271.1	DUF441 domain-containing protein	-
A6L48_RS10625 (A6L48_10625)	ispB	2027546..2028520 (-)	975	WP_002256366.1	octaprenyl diphosphate synthase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31363.39 Da
• Isoelectric Point: 8.2213

>NTDB_id=190427 A6L48_RS10595 WP_002223365.1 2023146..2024006(+) (pilD) [Neisseria meningitidis strain M22811]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLIAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLL
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGETGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=190427 A6L48_RS10595 WP_002223365.1 2023146..2024006(+) (pilD) [Neisseria meningitidis strain M22811]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGATCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCTC
TTGATTTGGCTGGGACTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	95.439	99.65	0.951
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Vibrio campbellii strain DS40M4	44.928	96.503	0.434
pilD	Acinetobacter baumannii D1279779	46.591	92.308	0.43
pilD	Acinetobacter nosocomialis M2	46.591	92.308	0.43