Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   A6L48_RS05280 Genome accession   NZ_CP016654
Coordinates   994936..995601 (+) Length   221 a.a.
NCBI ID   WP_002258536.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22811     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 989936..1000601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L48_RS05260 (A6L48_05260) - 990047..990379 (+) 333 WP_002213854.1 hypothetical protein -
  A6L48_RS05265 (A6L48_05265) - 990711..991220 (+) 510 WP_002213852.1 isoprenylcysteine carboxyl methyltransferase family protein -
  A6L48_RS05270 (A6L48_05270) - 992471..993058 (-) 588 WP_002258535.1 superoxide dismutase -
  A6L48_RS05275 (A6L48_05275) dnaB 993221..994627 (+) 1407 WP_002220671.1 replicative DNA helicase -
  A6L48_RS05280 (A6L48_05280) pilH 994936..995601 (+) 666 WP_002258536.1 GspH/FimT family pseudopilin Machinery gene
  A6L48_RS05285 (A6L48_05285) pilV 995631..996245 (+) 615 WP_002258537.1 type IV pilus modification protein PilV Machinery gene
  A6L48_RS05290 (A6L48_05290) pilJ 996242..997183 (+) 942 WP_002258538.1 PilW family protein Machinery gene
  A6L48_RS05295 (A6L48_05295) pilK 997162..997758 (+) 597 WP_002258539.1 pilus assembly PilX family protein Machinery gene
  A6L48_RS05300 (A6L48_05300) pilX 997763..998236 (+) 474 WP_002258540.1 PilX family type IV pilin Machinery gene

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24636.12 Da        Isoelectric Point: 9.7531

>NTDB_id=190408 A6L48_RS05280 WP_002258536.1 994936..995601(+) (pilH) [Neisseria meningitidis strain M22811]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTVN
NKCDSGKKGQGMLAFGDKNGNKTYDGDAADVFLRSVVLNDTDDSRINYAFNHIAFGSSQPTADRVVWTFNQNGTFGYTKD
QHLTSKSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNNRRTVCQYK

Nucleotide


Download         Length: 666 bp        

>NTDB_id=190408 A6L48_RS05280 WP_002258536.1 994936..995601(+) (pilH) [Neisseria meningitidis strain M22811]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGGTCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGACATATGACGGCGA
TGCGGCGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTATGCCTTCAACCATATCG
CTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAAGAC
CAGCATCTTACAAGCAAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACAATA
GGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.909

99.548

0.855

Multiple sequence alignment