Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L37_RS06615 Genome accession   NZ_CP016653
Coordinates   1266644..1267108 (-) Length   154 a.a.
NCBI ID   WP_025463168.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22748     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1264044..1277159 1266644..1267108 within 0
IS/Tn 1265115..1265768 1266644..1267108 flank 876


Gene organization within MGE regions


Location: 1264044..1277159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L37_RS06590 (A6L37_06590) - 1264502..1264759 (+) 258 WP_002241061.1 membrane protein -
  A6L37_RS06595 (A6L37_06595) - 1264741..1264950 (-) 210 Protein_1221 transposase -
  A6L37_RS06600 (A6L37_06600) - 1265115..1265768 (-) 654 WP_002241060.1 IS1595 family transposase -
  A6L37_RS06610 (A6L37_06610) - 1266326..1266532 (-) 207 WP_025461473.1 hypothetical protein -
  A6L37_RS06615 (A6L37_06615) comE 1266644..1267108 (-) 465 WP_025463168.1 ComEA family DNA-binding protein Machinery gene
  A6L37_RS06650 (A6L37_06650) - 1272907..1273713 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L37_RS06655 (A6L37_06655) ffh 1273933..1275303 (+) 1371 WP_002221448.1 signal recognition particle protein -
  A6L37_RS06660 (A6L37_06660) dsbA2 1275634..1276329 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L37_RS06665 (A6L37_06665) - 1276500..1277159 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16561.83 Da        Isoelectric Point: 10.9695

>NTDB_id=190368 A6L37_RS06615 WP_025463168.1 1266644..1267108(-) (comE) [Neisseria meningitidis strain M22748]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=190368 A6L37_RS06615 WP_025463168.1 1266644..1267108(-) (comE) [Neisseria meningitidis strain M22748]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment