Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6M06_RS10075 Genome accession   NZ_CP016651
Coordinates   1948838..1951927 (+) Length   1029 a.a.
NCBI ID   WP_079870587.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M25474     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1943838..1956927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M06_RS10040 (A6M06_10040) murU 1944245..1944940 (-) 696 WP_002221505.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -
  A6M06_RS10045 (A6M06_10045) hpaC 1944958..1945458 (-) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6M06_RS10050 (A6M06_10050) nadR 1945573..1946013 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6M06_RS10060 (A6M06_10060) - 1946356..1946865 (-) 510 WP_002259078.1 protein disulfide oxidoreductase -
  A6M06_RS10070 (A6M06_10070) apbC 1947230..1948309 (+) 1080 WP_002259079.1 iron-sulfur cluster carrier protein ApbC -
  A6M06_RS10075 (A6M06_10075) pilC 1948838..1951927 (+) 3090 WP_079870587.1 PilC family type IV pilus tip adhesin Machinery gene
  A6M06_RS10085 (A6M06_10085) carA 1953908..1955041 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6M06_RS10090 (A6M06_10090) - 1955087..1955224 (+) 138 WP_002214606.1 VOC family protein -
  A6M06_RS10105 (A6M06_10105) - 1955804..1956193 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6M06_RS13770 - 1956197..1956364 (+) 168 WP_153312129.1 hypothetical protein -

Sequence

Protein


Download         Length: 1029 a.a.        Molecular weight: 112976.45 Da        Isoelectric Point: 9.8184

>NTDB_id=190290 A6M06_RS10075 WP_079870587.1 1948838..1951927(+) (pilC) [Neisseria meningitidis strain M25474]
MNKTLKRQVFRHTALYAAILMFSHTGGGGAQAETRNYAIVMNEQNQPNVKQEGSYSTLREKDRKRKFDFNANRGGGGSVF
FDNTDTLVSQQRGTAVFGTATYLPPYGKVSGFDEKRLTERGNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYKTRFS
FDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGSPISL
GDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLRPRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKAGRCV
NANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIFLQNLKRKNDSNRPGRHSLETLTENDIKSRQ
PNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKEEN
NGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIQ
NTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKHDN
NGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLV
DKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDIQH
VYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKYED
NGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLD
EKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3090 bp        

>NTDB_id=190290 A6M06_RS10075 WP_079870587.1 1948838..1951927(+) (pilC) [Neisseria meningitidis strain M25474]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGGAAACCCGTAACTACGCTATTGTCATGAACGAACAAAATCAGCCGAATGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGAAACGCAAATTTGACTTTAATGCGAACAGAGGGGGTGGAGGTTCTGTCTTT
TTCGACAATACCGATACCCTTGTTTCCCAACAAAGAGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGCGGCAATGCCCTTAATTGGATTAATACGACCCACCCAGGGT
TGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAGCACAAGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCAACTCATTCA
ACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCCCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAGATTCA
AAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCTGGCTAAATTTTT
GGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGACCTGCCGGAAGTCAAAGCAGGCCGCTGCGTC
AACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCA
AAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCCTTCAAAATC
TGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGAACGATATTAAAAGTCGACAG
CCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGGCAATGAGGTCGC
CAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCACGCCTGATGCCAATGAGT
GGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAACAAAGAAGAAAAC
AACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAACGGCAAGCGTGATTTGGG
CGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCA
AACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAGGATATTCAA
AACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTACGGCGTGGACGG
CGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCAGAG
GCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTCAAACATGACAAT
AATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAA
ATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGCTGTATGTGTATG
ATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTG
GATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTAAGCGG
CAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCATTTCCCAAC
TGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAAGACATCCAACAC
GTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCTCGAGCAAGTGCT
TAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGTGGATGGTGAAAT
TGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATGAAGAC
AACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCC
GATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCATCCCTATAG
GTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGAC
GAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTC
CGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCG
GCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-837)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

81.13

100

0.823

Multiple sequence alignment