Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   A6M06_RS02870 Genome accession   NZ_CP016651
Coordinates   537889..538533 (+) Length   214 a.a.
NCBI ID   WP_002220358.1    Uniprot ID   A0A0U1RK99
Organism   Neisseria meningitidis strain M25474     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 532889..543533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M06_RS02845 (A6M06_02845) putP 533096..534622 (-) 1527 WP_002220352.1 sodium/proline symporter PutP -
  A6M06_RS02855 (A6M06_02855) - 535105..535425 (+) 321 WP_002216505.1 accessory factor UbiK family protein -
  A6M06_RS02860 (A6M06_02860) comM 535439..536935 (+) 1497 WP_002220355.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  A6M06_RS02865 (A6M06_02865) ftsN 537041..537886 (+) 846 WP_002220356.1 cell division protein FtsN -
  A6M06_RS02870 (A6M06_02870) dsbA1 537889..538533 (+) 645 WP_002220358.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6M06_RS02875 (A6M06_02875) - 538566..539387 (+) 822 WP_002220359.1 undecaprenyl-diphosphate phosphatase -
  A6M06_RS02890 (A6M06_02890) - 539960..541150 (-) 1191 WP_050584817.1 class I SAM-dependent methyltransferase -
  A6M06_RS02895 (A6M06_02895) mraZ 541456..541911 (+) 456 WP_002218779.1 division/cell wall cluster transcriptional repressor MraZ -
  A6M06_RS02900 (A6M06_02900) rsmH 541908..542894 (+) 987 WP_002220362.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
  A6M06_RS02905 (A6M06_02905) ftsL 542891..543154 (+) 264 WP_002220363.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23970.99 Da        Isoelectric Point: 10.0160

>NTDB_id=190262 A6M06_RS02870 WP_002220358.1 537889..538533(+) (dsbA1) [Neisseria meningitidis strain M25474]
MKLKHLLPLLLSAVLSAQAYALTEGEDYLVLDKPIPQKQSGKIEVLEFFGYFCVHCHHFDPLLLKLGKALPSDAYLRTEH
VVWQPEMLGLARMAAAVKLSGLKYQANPAVFKAVYEQKIRLENRSVAEKWALSQKGFDGKKLMRAYDSPAAAAAASKMQQ
LTEQYRIDSTPTVVVGGKYRVIFNNGFDGGVHTIKELVAKVREERKRQTPAVQK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=190262 A6M06_RS02870 WP_002220358.1 537889..538533(+) (dsbA1) [Neisseria meningitidis strain M25474]
ATGAAGCTCAAACATCTGTTGCCGCTGCTGCTGTCGGCAGTGTTGTCCGCGCAGGCATATGCCCTGACGGAAGGGGAAGA
CTATCTTGTGTTGGATAAACCCATTCCTCAAAAACAGTCGGGCAAAATTGAGGTTTTGGAATTTTTCGGCTATTTCTGCG
TACATTGCCATCATTTCGATCCTTTGTTATTGAAATTGGGCAAGGCATTGCCGTCTGATGCCTATTTAAGGACGGAGCAC
GTGGTCTGGCAGCCTGAAATGCTCGGTCTGGCAAGAATGGCTGCTGCGGTCAAGCTGTCAGGTTTGAAATATCAGGCAAA
CCCTGCCGTGTTTAAAGCAGTTTACGAACAAAAAATCCGCTTGGAAAACAGGTCGGTTGCCGAAAAATGGGCTTTGTCTC
AAAAAGGCTTTGACGGCAAAAAACTGATGCGCGCCTACGACTCTCCTGCGGCAGCGGCTGCTGCATCAAAAATGCAGCAA
TTGACGGAACAGTACCGCATCGACAGTACGCCGACCGTTGTCGTCGGCGGAAAATACCGCGTTATCTTCAATAATGGCTT
TGACGGCGGTGTTCATACGATTAAAGAATTGGTTGCCAAAGTCAGGGAAGAACGCAAGCGTCAGACCCCTGCTGTACAGA
AATAG

Domains

Predicted by InterproScan.

DSBA-like thioredoxin domain (DSBA)

(86-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RK99

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

55.851

87.85

0.491
  dsbA2 Neisseria meningitidis MC58

50.538

86.916

0.439

Multiple sequence alignment