Detailed information NTG0190013

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6L49_RS01260
• Genome accession: NZ_CP016646
• Coordinates: 248824..249684 (+)
• Length: 286 a.a.
• NCBI ID: WP_002223365.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22819
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 243824..254684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L49_RS01245 (A6L49_01245)	dapD	244334..245155 (-)	822	WP_002212339.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
A6L49_RS11570	-	245165..245395 (-)	231	WP_025462714.1	hypothetical protein	-
A6L49_RS01250 (A6L49_01250)	pgi	245365..247008 (-)	1644	WP_002220279.1	glucose-6-phosphate isomerase	-
A6L49_RS01255 (A6L49_01255)	pilG	247518..248750 (+)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
A6L49_RS01260 (A6L49_01260)	pilD	248824..249684 (+)	861	WP_002223365.1	prepilin peptidase	Machinery gene
A6L49_RS01265 (A6L49_01265)	coaE	249686..250318 (+)	633	WP_002258461.1	dephospho-CoA kinase	-
A6L49_RS01270 (A6L49_01270)	-	250311..250520 (+)	210	WP_002226982.1	DNA gyrase inhibitor YacG	-
A6L49_RS01275 (A6L49_01275)	pilF	250605..252281 (-)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6L49_RS01285 (A6L49_01285)	-	252773..253219 (-)	447	WP_002220271.1	DUF441 domain-containing protein	-
A6L49_RS01290 (A6L49_01290)	ispB	253224..254198 (-)	975	WP_002256366.1	octaprenyl diphosphate synthase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31363.39 Da
• Isoelectric Point: 8.2213

>NTDB_id=190013 A6L49_RS01260 WP_002223365.1 248824..249684(+) (pilD) [Neisseria meningitidis strain M22819]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLIAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLL
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGETGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=190013 A6L49_RS01260 WP_002223365.1 248824..249684(+) (pilD) [Neisseria meningitidis strain M22819]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGATCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCTC
TTGATTTGGCTGGGACTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	95.439	99.65	0.951
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Vibrio campbellii strain DS40M4	44.928	96.503	0.434
pilD	Acinetobacter baumannii D1279779	46.591	92.308	0.43
pilD	Acinetobacter nosocomialis M2	46.591	92.308	0.43