Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L28_RS10435 Genome accession   NZ_CP016645
Coordinates   2014051..2017152 (+) Length   1033 a.a.
NCBI ID   WP_079884489.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M12752     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2009051..2022152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L28_RS10405 (A6L28_10405) hpaC 2009761..2010261 (-) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6L28_RS10410 (A6L28_10410) nadR 2010376..2010816 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L28_RS10420 (A6L28_10420) - 2011159..2011668 (-) 510 WP_002225670.1 protein disulfide oxidoreductase -
  A6L28_RS10430 (A6L28_10430) apbC 2012033..2013112 (+) 1080 WP_002248347.1 iron-sulfur cluster carrier protein ApbC -
  A6L28_RS10435 (A6L28_10435) pilC 2014051..2017152 (+) 3102 WP_079884489.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L28_RS10445 (A6L28_10445) carA 2019109..2020242 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L28_RS10450 (A6L28_10450) - 2020288..2020425 (+) 138 WP_002214606.1 VOC family protein -
  A6L28_RS10465 (A6L28_10465) - 2021005..2021394 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L28_RS13805 - 2021398..2021565 (+) 168 WP_153312129.1 hypothetical protein -

Sequence

Protein


Download         Length: 1033 a.a.        Molecular weight: 113169.68 Da        Isoelectric Point: 9.8243

>NTDB_id=190005 A6L28_RS10435 WP_079884489.1 2014051..2017152(+) (pilC) [Neisseria meningitidis strain M12752]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGGGAMAQTHKYAIIMNEGNQPEVKQNGQYSTIKDKDREREYTYHQGTRGGG
GSVSFNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDEKRLTERGNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYK
TRFSFDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGS
PISLGDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLRPRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKA
GRCVNANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIFLQNLKRKNDSNRPGRHSLETLTENDI
KSRQPNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVN
KEENNGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPR
KDIQNTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDV
KHDNNGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSS
PTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNK
DIQHVYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIR
KYKDNGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNV
RYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3102 bp        

>NTDB_id=190005 A6L28_RS10435 WP_079884489.1 2014051..2017152(+) (pilC) [Neisseria meningitidis strain M12752]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTAAAGC
AGAATGGGCAATATTCAACAATAAAGGACAAAGACAGGGAGCGCGAATATACTTATCATCAGGGCACAAGAGGAGGAGGA
GGCTCTGTCTCATTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCT
GCCGCCCTACGGCAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGCGGCAATGCCCTTAATTGGATTAATACGA
CCCACCCAGGGTTGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAGCACAAGCTGTCCCAAACTTGTCTATAAA
ACCCGATTTTCCTTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGGATAGGCACCCGGACCCAAGCCGCGAAAA
TTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATG
GCAACTCATTCAACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCC
CCTATTTCCCTTGGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAA
AAAACAGATTCAAAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCT
GGCTAAATTTTTGGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGACCTGCCGGAAGTCAAAGCA
GGCCGCTGCGTCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACCGCCCCCGCGCTGTGGTT
CGGCCCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCT
TCCTTCAAAATCTGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGAACGATATT
AAAAGTCGACAGCCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGG
CAATGAGGTCGCCAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCACGCCTG
ATGCCAATGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAAC
AAAGAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAACGGCAA
GCGTGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGG
TGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGC
AAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTA
CGGCGTGGACGGCGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTT
TTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTC
AAACATGACAATAATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAAC
CCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGC
TGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCC
CCCACGCTGGTGGATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTT
TGATTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCG
CCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAA
GACATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCT
CGAGCAAGTGCTTAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGT
GGATGGTGAAATTGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGC
AAATATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAA
AAGCGCGCGCCCGATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAAT
CCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTG
CGCTACCTGGACGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGC
CGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCT
TGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(510-841)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

81.107

100

0.823

Multiple sequence alignment