Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B9L64_RS09005 Genome accession   NZ_CP020915
Coordinates   1757280..1757915 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain 50-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1752280..1762915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B9L64_RS08985 yvzF 1753337..1753522 (-) 186 WP_003244599.1 YvzF family protein -
  B9L64_RS08990 gerAA 1753640..1755088 (+) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  B9L64_RS08995 gerAB 1755057..1756154 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  B9L64_RS09000 gerAC 1756151..1757272 (+) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  B9L64_RS09005 vraR 1757280..1757915 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  B9L64_RS09010 liaS 1757893..1758975 (-) 1083 WP_015251253.1 two-component system sensor histidine kinase LiaS -
  B9L64_RS09015 liaF 1758972..1759697 (-) 726 WP_014480832.1 LiaRS two-component regulatory system accessory protein LiaF -
  B9L64_RS09020 liaG 1759731..1760603 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  B9L64_RS09025 liaH 1760704..1761381 (-) 678 WP_003243047.1 stress responsive protein LiaH -
  B9L64_RS09030 liaI 1761408..1761788 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=189799 B9L64_RS09005 WP_003243201.1 1757280..1757915(-) (vraR) [Bacillus subtilis strain 50-1]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=189799 B9L64_RS09005 WP_003243201.1 1757280..1757915(-) (vraR) [Bacillus subtilis strain 50-1]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408

Multiple sequence alignment