Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L32_RS05225 Genome accession   NZ_CP016627
Coordinates   1005586..1006050 (+) Length   154 a.a.
NCBI ID   WP_025463168.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22718     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1006926..1007579 1005586..1006050 flank 876


Gene organization within MGE regions


Location: 1005586..1007579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L32_RS05225 (A6L32_05225) comE 1005586..1006050 (+) 465 WP_025463168.1 ComEA family DNA-binding protein Machinery gene
  A6L32_RS12180 - 1006162..1006368 (+) 207 WP_025461473.1 hypothetical protein -
  A6L32_RS05235 (A6L32_05235) - 1006926..1007579 (+) 654 WP_002241060.1 IS1595 family transposase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16561.83 Da        Isoelectric Point: 10.9695

>NTDB_id=189776 A6L32_RS05225 WP_025463168.1 1005586..1006050(+) (comE) [Neisseria meningitidis strain M22718]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=189776 A6L32_RS05225 WP_025463168.1 1005586..1006050(+) (comE) [Neisseria meningitidis strain M22718]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment