Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B7474_RS08280 Genome accession   NZ_CP020714
Coordinates   1613900..1614523 (+) Length   207 a.a.
NCBI ID   WP_001045130.1    Uniprot ID   -
Organism   Staphylococcus aureus strain K18     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1608900..1619523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7474_RS08260 (B7474_08270) - 1609354..1609749 (+) 396 WP_000901023.1 hypothetical protein -
  B7474_RS08265 (B7474_08275) fumC 1609945..1611330 (+) 1386 WP_000116229.1 class II fumarate hydratase -
  B7474_RS08270 (B7474_08280) - 1611782..1612603 (-) 822 WP_000669376.1 RluA family pseudouridine synthase -
  B7474_RS08275 (B7474_08285) - 1612766..1613878 (+) 1113 WP_000437970.1 GAF domain-containing sensor histidine kinase -
  B7474_RS08280 (B7474_08290) vraR 1613900..1614523 (+) 624 WP_001045130.1 response regulator Regulator
  B7474_RS08285 (B7474_08295) - 1614879..1615343 (+) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  B7474_RS08290 (B7474_08300) - 1615522..1616646 (+) 1125 WP_101766560.1 DUF445 domain-containing protein -
  B7474_RS08295 (B7474_08305) - 1616715..1617059 (+) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  B7474_RS08305 (B7474_08315) - 1617553..1617651 (+) 99 WP_031774968.1 hypothetical protein -
  B7474_RS08310 (B7474_08320) - 1617948..1619144 (+) 1197 WP_000238221.1 metallophosphoesterase family protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23953.60 Da        Isoelectric Point: 5.3526

>NTDB_id=189332 B7474_RS08280 WP_001045130.1 1613900..1614523(+) (vraR) [Staphylococcus aureus strain K18]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPDMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=189332 B7474_RS08280 WP_001045130.1 1613900..1614523(+) (vraR) [Staphylococcus aureus strain K18]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGACATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.063

100

0.411
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377