Detailed information NTG0188223

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: BAY21_RS00480
• Genome accession: NZ_CP016439
• Coordinates: 90478..91317 (-)
• Length: 279 a.a.
• NCBI ID: WP_011227155.1
• Uniprot ID: A0A3G6JMX3
• Organism: Streptococcus thermophilus strain CS8
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 85478..96317

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BAY21_RS00465 (BAY21_00465)	-	86530..87189 (-)	660	WP_011227158.1	response regulator transcription factor	-
BAY21_RS00470 (BAY21_00470)	-	87225..88049 (-)	825	WP_011227157.1	TraX family protein	-
BAY21_RS00475 (BAY21_00475)	topA	88166..90310 (-)	2145	WP_011227156.1	type I DNA topoisomerase	-
BAY21_RS00480 (BAY21_00480)	dprA	90478..91317 (-)	840	WP_011227155.1	DNA-processing protein DprA	Machinery gene
BAY21_RS00485 (BAY21_00485)	-	91385..92305 (-)	921	WP_002950604.1	ROK family protein	-
BAY21_RS00490 (BAY21_00490)	-	92316..93083 (-)	768	WP_041827018.1	ribonuclease HII	-
BAY21_RS00495 (BAY21_00495)	ylqF	93070..93924 (-)	855	WP_002950602.1	ribosome biogenesis GTPase YlqF	-
BAY21_RS00500 (BAY21_00500)	-	94052..94741 (-)	690	WP_011225885.1	XRE family transcriptional regulator	-
BAY21_RS00505 (BAY21_00505)	-	94836..95351 (-)	516	WP_011225884.1	transcription repressor NadR	-
BAY21_RS00510 (BAY21_00510)	-	95375..95902 (-)	528	WP_041827017.1	ECF transporter S component	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31233.11 Da
• Isoelectric Point: 8.4489

>NTDB_id=188223 BAY21_RS00480 WP_011227155.1 90478..91317(-) (dprA) [Streptococcus thermophilus strain CS8]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVNQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHYPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDIISEFS

Nucleotide

• Length: 840 bp

>NTDB_id=188223 BAY21_RS00480 WP_011227155.1 90478..91317(-) (dprA) [Streptococcus thermophilus strain CS8]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTGACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAATCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCAGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCATATGGAGGCCTTAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGGGTGAACAGCCACTTAAATACCATTATCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGGGTTATGGTGGTTGAAGCCAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGAAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATCACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAATTTTCATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A3G6JMX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	71.685	100	0.717
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus mitis SK321	62.95	99.642	0.627
dprA	Lactococcus lactis subsp. cremoris KW2	60.072	99.642	0.599
dprA	Latilactobacillus sakei subsp. sakei 23K	39.768	92.832	0.369
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75.269	0.362