Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   clem_RS10580 Genome accession   NZ_CP016397
Coordinates   2412775..2413434 (-) Length   219 a.a.
NCBI ID   WP_094091528.1    Uniprot ID   A0A222P4C8
Organism   Legionella clemsonensis strain CDC-D5610     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2407775..2418434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  clem_RS10565 (clem_10735) - 2409387..2409917 (-) 531 WP_198333114.1 endopeptidase IV -
  clem_RS10570 (clem_10740) - 2409914..2410642 (-) 729 WP_094091526.1 L,D-transpeptidase -
  clem_RS10575 (clem_10745) uvrC 2410845..2412689 (-) 1845 WP_094091527.1 excinuclease ABC subunit UvrC -
  clem_RS10580 (clem_10750) letA 2412775..2413434 (-) 660 WP_094091528.1 two-component system response regulator LetA Regulator
  clem_RS10585 (clem_10755) phhA 2413653..2414471 (-) 819 WP_094091529.1 phenylalanine 4-monooxygenase -
  clem_RS10590 (clem_10760) bioC 2414597..2415463 (-) 867 WP_094091530.1 malonyl-ACP O-methyltransferase BioC -
  clem_RS10595 (clem_10765) comFC 2415499..2416194 (+) 696 WP_157698233.1 ComF family protein Machinery gene
  clem_RS10600 (clem_10770) - 2416191..2416907 (-) 717 WP_094091531.1 hypothetical protein -
  clem_RS10605 (clem_10780) - 2417027..2418093 (-) 1067 Protein_2118 M50 family metallopeptidase -
  clem_RS10610 (clem_10785) - 2418098..2418385 (-) 288 WP_094091532.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24447.59 Da        Isoelectric Point: 5.3953

>NTDB_id=187976 clem_RS10580 WP_094091528.1 2412775..2413434(-) (letA) [Legionella clemsonensis strain CDC-D5610]
MIKVLIVDDHALVRMGIRRLLEDLPDVEVVADAESGELALALVKSHKPDVVLLDMKMPGIDGWEVTRRLKKSNPQVKVIA
VTAMCADPIPTRVLQLGAMGYLTKESGAEEMAAAIRKVARGEKYLSAEIAQQMAINSLEAPQDSPFDLLSEREMQVMLMI
TSGMTVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTFLAMKHRVIEQPNDALHNE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=187976 clem_RS10580 WP_094091528.1 2412775..2413434(-) (letA) [Legionella clemsonensis strain CDC-D5610]
TTGATAAAAGTTCTAATTGTTGATGACCATGCCCTGGTAAGAATGGGGATTCGACGATTATTGGAGGATCTGCCGGATGT
AGAGGTGGTTGCTGATGCTGAAAGTGGTGAATTAGCTTTGGCATTAGTAAAATCTCATAAGCCCGATGTGGTATTACTTG
ACATGAAAATGCCTGGAATTGACGGATGGGAGGTAACCCGAAGGCTTAAGAAATCTAATCCACAAGTTAAGGTCATTGCT
GTAACAGCCATGTGTGCCGATCCGATCCCTACTCGTGTTCTCCAGCTTGGTGCTATGGGCTATTTGACCAAAGAGTCTGG
TGCTGAAGAAATGGCTGCTGCGATTCGCAAAGTAGCTAGAGGCGAAAAATATTTGAGTGCTGAAATCGCGCAACAAATGG
CAATTAATAGTTTGGAAGCCCCACAGGATTCACCTTTTGATCTCTTGTCTGAACGTGAAATGCAAGTCATGCTAATGATT
ACCAGTGGCATGACGGTGCAAGATATCGCTGACAGATTGTTTTTAAGTTCGAAAACCATTAATGGCTATCGTTATCGAAT
GTTTGAAAAATTAGGCATTAAAAATGATGTGGAGCTCACTTTTCTGGCAATGAAACATCGAGTCATTGAGCAGCCTAATG
ATGCTTTGCATAATGAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A222P4C8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

90.187

97.717

0.881
  letA Legionella pneumophila strain ERS1305867

90.187

97.717

0.881

Multiple sequence alignment