Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   clem_RS08600 Genome accession   NZ_CP016397
Coordinates   1978854..1981070 (-) Length   738 a.a.
NCBI ID   WP_094091175.1    Uniprot ID   A0A222P393
Organism   Legionella clemsonensis strain CDC-D5610     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1973854..1986070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  clem_RS08575 (clem_08725) - 1974029..1974697 (-) 669 WP_013101291.1 SOS response-associated peptidase -
  clem_RS08580 (clem_08730) - 1975180..1976247 (-) 1068 WP_011213398.1 hypothetical protein -
  clem_RS08585 (clem_08735) - 1976319..1977077 (-) 759 WP_027266381.1 2OG-Fe(II) oxygenase -
  clem_RS08595 (clem_08745) - 1977610..1978767 (-) 1158 WP_094092317.1 multidrug DMT transporter permease -
  clem_RS08600 (clem_08750) comEC 1978854..1981070 (-) 2217 WP_094091175.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  clem_RS08605 (clem_08755) - 1981357..1982481 (+) 1125 WP_094091176.1 Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha -
  clem_RS08610 (clem_08760) - 1982474..1982770 (+) 297 WP_058448949.1 proton-translocating transhydrogenase family protein -
  clem_RS08615 (clem_08765) - 1982837..1984231 (+) 1395 WP_198333089.1 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta -
  clem_RS08620 (clem_08770) - 1984383..1984763 (+) 381 WP_094091178.1 hypothetical protein -

Sequence

Protein


Download         Length: 738 a.a.        Molecular weight: 82454.11 Da        Isoelectric Point: 9.8713

>NTDB_id=187973 clem_RS08600 WP_094091175.1 1978854..1981070(-) (comEC) [Legionella clemsonensis strain CDC-D5610]
MEILCFFAGTVFFYTKSVYAILLVVVAFFLSPRLSFPCCFLAALLWGYAHQWWVADCGMPMHVRIIPHAVLEGEIVSIPA
TTTFKSQFQFKLSKFNGKPASSILLLACYNRCPLFKVGESWRFEAKIKKPANLGNPGSFNYVNWLSARHIHWVGYIKPRT
ATLLKPGQSSSLLRLREQLASTLDKLLPEGKSLGIFEALTLGITNHIDKSQWELFRRTGTTHLMVISGAHIGLVAGLGFM
LMRWLWTRNAWLCLHYPAPQAASIAGLLMAIAYALLAGFAPPAQRSLIACFLLLSRNFSSYRFTGWQAWRYGLLAVLLFE
PHDVLLPGFYLSFLAVASLLLGSQRLRATGFKKSLGLQLICLFGLMPLTLFWFSYGAISGLLANLVAIPFVGFVIVPAAL
ISLLAVQCWDEAWFLIPVHWAIEVLLYFLKLIDSLASFNLSFSFSSILSPLALMLVMLSGLFLPVRAFYPAMIVLGMAAL
YPGYPKVRGGEAEINILDVGQGLAVTVRTANHTLVYDTGMKFYQGGDMAKLAIIPFLKTVGIKKIDKIIISHPDLDHRGG
LVSLETNYPVNALLVNNISYYRRGENCHYYPSWQWDGISFRFLAIHKRFKNKNNNSCILQIGNSRGRILLTGDIERSAED
YLVKMYKEQLASEVLVVPHHGSKTSSSPSFIQQISPKFAVISAGFDNRYHFPHAQTLQTFARQNVKILSTADCGMVTVRL
PANHDRINPFCYKTITSA

Nucleotide


Download         Length: 2217 bp        

>NTDB_id=187973 clem_RS08600 WP_094091175.1 1978854..1981070(-) (comEC) [Legionella clemsonensis strain CDC-D5610]
ATGGAAATTCTCTGTTTTTTTGCAGGGACGGTCTTTTTTTATACAAAGTCAGTCTATGCCATTTTACTGGTGGTTGTTGC
ATTTTTTCTCTCCCCTCGGTTGAGTTTTCCCTGTTGCTTTCTTGCAGCTCTGCTGTGGGGATATGCTCACCAGTGGTGGG
TGGCCGATTGTGGCATGCCGATGCACGTTCGCATTATCCCACATGCTGTTTTAGAAGGTGAAATTGTATCCATCCCAGCA
ACAACGACTTTTAAGTCTCAGTTCCAGTTTAAACTGTCGAAGTTTAATGGGAAACCTGCTAGCTCTATCTTGCTATTGGC
CTGTTATAATCGCTGCCCTTTATTTAAAGTGGGAGAATCTTGGCGTTTTGAAGCAAAAATAAAAAAACCAGCGAATCTGG
GAAATCCAGGCAGTTTTAATTATGTAAATTGGTTAAGTGCTCGTCATATTCATTGGGTGGGGTATATTAAACCGCGCACT
GCCACGCTCCTAAAACCTGGTCAATCTTCAAGTCTTTTAAGACTTCGTGAGCAGCTTGCGTCAACTCTCGATAAACTATT
ACCTGAAGGAAAAAGTCTGGGCATTTTTGAAGCATTAACGCTGGGTATTACCAATCATATTGATAAGTCACAGTGGGAGT
TGTTTCGCCGAACAGGAACTACTCATTTGATGGTCATTTCCGGTGCTCACATTGGTTTGGTGGCAGGATTAGGATTTATG
TTAATGCGATGGTTATGGACTCGAAATGCATGGCTATGTCTTCATTATCCAGCACCTCAGGCAGCCAGTATTGCAGGATT
GCTAATGGCTATCGCTTATGCACTACTCGCTGGATTTGCTCCTCCCGCCCAACGTTCACTTATTGCTTGTTTTTTATTGC
TCTCGAGAAATTTTTCAAGTTATCGCTTTACCGGCTGGCAAGCTTGGCGCTATGGCTTATTAGCAGTATTACTTTTTGAA
CCGCATGATGTTTTATTGCCAGGATTCTATTTATCCTTTCTTGCTGTAGCCAGTTTGCTGTTAGGCAGTCAACGATTAAG
AGCTACAGGTTTTAAAAAAAGCCTGGGGTTGCAGCTTATTTGTCTTTTCGGATTAATGCCTCTAACATTGTTTTGGTTCT
CTTATGGGGCAATTAGTGGGTTGCTAGCCAATCTGGTTGCTATTCCGTTTGTAGGATTTGTTATCGTCCCTGCTGCGCTT
ATCAGTTTGTTGGCAGTGCAATGTTGGGATGAGGCCTGGTTTTTAATACCAGTACACTGGGCGATTGAGGTTTTGCTTTA
TTTTTTAAAATTGATTGACTCCTTGGCATCATTTAATTTGAGCTTTTCCTTTAGCAGTATTTTATCGCCTTTAGCATTGA
TGCTGGTCATGTTGTCAGGCTTATTTCTCCCTGTTAGGGCATTTTACCCAGCAATGATTGTGTTGGGTATGGCGGCTCTT
TATCCAGGATATCCTAAAGTGAGGGGAGGGGAGGCTGAAATTAATATTCTTGATGTGGGGCAAGGTTTAGCAGTGACTGT
ACGAACAGCCAATCACACGCTTGTTTATGATACCGGAATGAAATTCTATCAGGGTGGGGATATGGCAAAATTGGCGATTA
TTCCTTTTCTTAAAACTGTGGGGATAAAGAAGATTGATAAAATTATTATTAGCCATCCCGATTTAGATCACCGAGGTGGC
CTTGTTTCGCTGGAAACTAATTATCCAGTCAATGCGCTTTTGGTCAATAATATTTCCTATTATCGTCGAGGAGAAAATTG
CCATTACTATCCCTCGTGGCAATGGGATGGCATTTCTTTTCGTTTTTTAGCTATTCATAAACGGTTTAAAAACAAGAATA
ATAACTCGTGTATTTTGCAAATTGGGAATTCCAGAGGGCGTATTTTATTAACAGGGGATATAGAACGGTCAGCGGAAGAC
TATTTGGTAAAAATGTACAAAGAACAACTTGCATCCGAAGTATTAGTTGTCCCTCACCATGGCAGCAAAACATCTTCCTC
ACCTAGCTTCATTCAACAAATTTCACCAAAATTTGCAGTAATATCCGCAGGCTTTGATAATCGATATCATTTTCCGCATG
CGCAAACATTGCAAACTTTTGCACGACAAAATGTGAAAATATTGAGTACTGCAGATTGTGGCATGGTCACCGTGCGATTG
CCTGCAAACCATGACAGGATAAACCCATTTTGTTATAAAACAATAACAAGTGCATAA

Domains

Predicted by InterProScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-684)

Domain of unknown function (DUF4131) (DUF4131)

(20-159)

Competence protein (Competence)

(199-463)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

49.798

100

0.5
  comEC Legionella pneumophila strain ERS1305867

49.324

100

0.495

Multiple sequence alignment