Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B6R96_RS19665 Genome accession   NZ_CP020555
Coordinates   4387109..4387729 (-) Length   206 a.a.
NCBI ID   WP_030387306.1    Uniprot ID   -
Organism   Streptomyces sp. Sge12     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4382109..4392729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B6R96_RS19635 (B6R96_19635) - 4382209..4383102 (+) 894 WP_081523075.1 aminoglycoside phosphotransferase family protein -
  B6R96_RS19640 (B6R96_19640) - 4383112..4383588 (+) 477 WP_081523076.1 GNAT family N-acetyltransferase -
  B6R96_RS19645 (B6R96_19645) - 4383595..4384587 (-) 993 WP_081525163.1 zinc-binding dehydrogenase -
  B6R96_RS19650 (B6R96_19650) - 4384683..4385375 (+) 693 WP_081523077.1 pentapeptide repeat-containing protein -
  B6R96_RS19655 (B6R96_19655) - 4385494..4386492 (+) 999 Protein_3860 glycosyl hydrolase -
  B6R96_RS19660 (B6R96_19660) - 4386560..4387063 (-) 504 WP_079405330.1 hypothetical protein -
  B6R96_RS19665 (B6R96_19665) vraR 4387109..4387729 (-) 621 WP_030387306.1 response regulator transcription factor Regulator
  B6R96_RS19670 (B6R96_19670) - 4387726..4388970 (-) 1245 WP_081523079.1 sensor histidine kinase -
  B6R96_RS19675 (B6R96_19675) - 4389246..4389803 (+) 558 WP_081523080.1 heme-binding protein -
  B6R96_RS19680 (B6R96_19680) - 4389836..4391248 (+) 1413 WP_081523081.1 M1 family metallopeptidase -
  B6R96_RS19685 (B6R96_19685) - 4391316..4391834 (-) 519 WP_081523082.1 GNAT family N-acetyltransferase -
  B6R96_RS19690 (B6R96_19690) - 4391980..4392555 (-) 576 WP_030387311.1 TerD family protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21774.06 Da        Isoelectric Point: 5.6407

>NTDB_id=187611 B6R96_RS19665 WP_030387306.1 4387109..4387729(-) (vraR) [Streptomyces sp. Sge12]
MTTILLCDDHVVVRAGLLALLGSEPDIEVLGEAGSGEEAVALAAKLGPDVVLMDLQLGEGIDGVEATRRITALPRPPHVL
VLTTYDTDADITRAIGAGATGYLLKAERPEELFAAIHSAAQGRTTLSAPVASRVMAHMRGTRPTLTDRELDILGQLARGL
GNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 621 bp        

>NTDB_id=187611 B6R96_RS19665 WP_030387306.1 4387109..4387729(-) (vraR) [Streptomyces sp. Sge12]
ATGACGACGATCCTCCTGTGCGACGACCACGTCGTGGTCCGCGCCGGGCTGCTGGCCCTGCTCGGCAGCGAGCCGGACAT
CGAGGTCCTCGGCGAGGCGGGCAGCGGTGAGGAGGCGGTCGCCCTCGCCGCGAAACTCGGCCCCGACGTGGTCCTGATGG
ACCTCCAGCTGGGCGAGGGCATCGACGGGGTCGAGGCCACCCGCCGCATCACCGCGCTCCCCCGGCCCCCGCACGTCCTG
GTCCTCACCACGTACGACACGGACGCGGACATCACCCGGGCGATCGGCGCGGGCGCCACCGGCTACCTCCTCAAGGCCGA
ACGCCCCGAGGAGCTCTTCGCCGCCATTCACTCCGCGGCCCAGGGCCGCACCACCCTGTCCGCACCGGTGGCCAGCCGGG
TGATGGCCCACATGCGCGGCACCCGCCCCACCCTGACCGACCGCGAACTGGACATCCTCGGCCAGCTGGCCCGGGGCCTG
GGCAACCGCGACATCGCCCGCGCCCTGTTCATCAGCGAGGCCACGGTCAAGACCCACCTGGGCCGCATCTACGACAAGCT
CGGCGTCGACACCCGCGCGGGCGCGGTCTCGGTGGCCAAGGAACAGCGCCTGCTGCCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(144-199)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.32

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

35.023

100

0.369