Detailed information NTG0187217

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: A9P12_RS24240
• Genome accession: NZ_CP020514
• Coordinates: 4723160..4724185 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain 219
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4718160..4729185

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9P12_RS24220 (A9P12_24165)	metJ	4719221..4719538 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
A9P12_RS24225 (A9P12_24170)	yiiX	4719722..4720330 (+)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
A9P12_RS24230 (A9P12_24175)	rpmE	4720391..4720603 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
A9P12_RS24235 (A9P12_24180)	priA	4720806..4723004 (+)	2199	WP_001333520.1	primosomal protein N'	Machinery gene
A9P12_RS24240 (A9P12_24185)	cytR	4723160..4724185 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
A9P12_RS24245 (A9P12_24190)	ftsN	4724277..4725236 (+)	960	WP_000068828.1	cell division protein FtsN	-
A9P12_RS24250 (A9P12_24195)	hslV	4725329..4725859 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
A9P12_RS24255 (A9P12_24200)	hslU	4725869..4727200 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
A9P12_RS24260 (A9P12_24205)	menA	4727267..4728193 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
A9P12_RS24265 (A9P12_24210)	rraA	4728286..4728771 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
A9P12_RS24270 (A9P12_24215)	zapB	4728856..4729101 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=187217 A9P12_RS24240 WP_000644904.1 4723160..4724185(+) (cytR) [Escherichia coli strain 219]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=187217 A9P12_RS24240 WP_000644904.1 4723160..4724185(+) (cytR) [Escherichia coli strain 219]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628