Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A6J87_RS08240 Genome accession   NZ_CP020451
Coordinates   1605664..1606308 (+) Length   214 a.a.
NCBI ID   WP_002891417.1    Uniprot ID   J7TMS3
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1600664..1611308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS08220 (A6J87_08190) stkP/pknB 1601029..1602903 (+) 1875 WP_037601769.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J87_RS08225 (A6J87_08195) - 1603048..1603806 (+) 759 WP_073950478.1 potassium channel family protein -
  A6J87_RS08230 (A6J87_08200) liaF 1603969..1604667 (+) 699 WP_037603001.1 cell wall-active antibiotics response protein LiaF -
  A6J87_RS08235 (A6J87_08205) - 1604664..1605674 (+) 1011 WP_002891418.1 sensor histidine kinase -
  A6J87_RS08240 (A6J87_08210) vraR 1605664..1606308 (+) 645 WP_002891417.1 response regulator transcription factor Regulator
  A6J87_RS08255 (A6J87_08225) rimM 1607003..1607521 (+) 519 WP_060971504.1 ribosome maturation factor RimM -
  A6J87_RS08260 (A6J87_08230) trmD 1607511..1608230 (+) 720 WP_002886864.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  A6J87_RS08265 (A6J87_08235) - 1608232..1609230 (+) 999 WP_060971505.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24007.33 Da        Isoelectric Point: 4.5814

>NTDB_id=186795 A6J87_RS08240 WP_002891417.1 1605664..1606308(+) (vraR) [Streptococcus salivarius strain FDAARGOS_259]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEASNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=186795 A6J87_RS08240 WP_002891417.1 1605664..1606308(+) (vraR) [Streptococcus salivarius strain FDAARGOS_259]
ATGTCGAATAAGATAAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGCCTTAAGAGTTTCCTGAATCTCCA
AGGAGATGTCGAAGTGGTTGGAGAAGCGAGCAATGGCCGAGAAGGTGTTGACCTTGCCCTGGAACTTCGTCCAGATGTCG
TCGTAATGGACCTTGTCATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCAGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGTGCTAAAGGTTATATGCTTAA
AACTAGCAGTGCGGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACAGAGGTGGACA
ATAAGATTAAATACCACGATAGCCATCCGGACCTACACGATGACTTAACGGCACGTGAACGTGATATCCTGGCACTTTTG
GCTAAGGGTTATGACAATCAGACCATTGCTAACGAGCTATTCATTTCATTGAAAACCGTTAAAACTCACGTGTCTAATAT
CCTAGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTTGTTTATGCCTTTAGACATCATTTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TMS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379