Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A6J87_RS03000 Genome accession   NZ_CP020451
Coordinates   608998..610317 (-) Length   439 a.a.
NCBI ID   WP_080611551.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 603998..615317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS02990 (A6J87_02975) hpf 607728..608276 (-) 549 WP_080611550.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  A6J87_RS02995 (A6J87_02980) comFC/cflB 608355..609017 (-) 663 WP_002883740.1 ComF family protein Machinery gene
  A6J87_RS03000 (A6J87_02985) comFA/cflA 608998..610317 (-) 1320 WP_080611551.1 DEAD/DEAH box helicase Machinery gene
  A6J87_RS03005 (A6J87_02990) - 610372..610998 (+) 627 WP_038675335.1 YigZ family protein -
  A6J87_RS03010 (A6J87_02995) cysK 611100..612026 (+) 927 WP_002883742.1 cysteine synthase A -
  A6J87_RS03015 (A6J87_03000) - 612176..612835 (-) 660 WP_002890017.1 CBS and ACT domain-containing protein -
  A6J87_RS03020 (A6J87_03005) - 612970..613680 (-) 711 WP_002883761.1 ABC transporter ATP-binding protein -
  A6J87_RS03025 (A6J87_03010) - 613680..614444 (-) 765 WP_021143582.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50645.62 Da        Isoelectric Point: 8.9020

>NTDB_id=186727 A6J87_RS03000 WP_080611551.1 608998..610317(-) (comFA/cflA) [Streptococcus salivarius strain FDAARGOS_259]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKKLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGSLEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQNYLPDEKMAFVSSKSEERSATVENFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=186727 A6J87_RS03000 WP_080611551.1 608998..610317(-) (comFA/cflA) [Streptococcus salivarius strain FDAARGOS_259]
ATGGTACCTAAAGAATATTATGGACGGCTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAAAAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCGTGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCAGAAATTGAGTTTCCTGTTTTGAAGTGGTTGGGAGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGATCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTCACTAGCATT
CTACAAAACTATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGTGAGGAGCGTTCAGCTACCGTAGAGAACTT
CCGAGAAAAAGAGTTATCCATTTTAGTGACAACAACTATCCTCGAACGTGGTGTGACCTTTCCACAAGTAGATGTTTTTG
TTTGCATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCTCCAGATAGA
CCGACAGGGAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae D39

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae R6

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae TIGR4

56.613

98.178

0.556
  comFA/cflA Streptococcus mitis NCTC 12261

55.76

98.861

0.551
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.844

99.317

0.376