Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B4U62_RS17865 Genome accession   NZ_CP020102
Coordinates   3394437..3395072 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain NCIB 3610     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3389437..3400072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B4U62_RS17845 (B4U62_17845) yvzF 3390494..3390679 (-) 186 WP_003244599.1 YvzF family protein -
  B4U62_RS17850 (B4U62_17850) gerAA 3390797..3392245 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  B4U62_RS17855 (B4U62_17855) gerAB 3392214..3393311 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  B4U62_RS17860 (B4U62_17860) gerAC 3393308..3394429 (+) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  B4U62_RS17865 (B4U62_17865) vraR 3394437..3395072 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  B4U62_RS17870 (B4U62_17870) liaS 3395050..3396132 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  B4U62_RS17875 (B4U62_17875) liaF 3396129..3396854 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  B4U62_RS17880 (B4U62_17880) liaG 3396888..3397760 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  B4U62_RS17885 (B4U62_17885) liaH 3397861..3398538 (-) 678 WP_003243047.1 stress responsive protein LiaH -
  B4U62_RS17890 (B4U62_17890) liaI 3398565..3398945 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=184906 B4U62_RS17865 WP_003243201.1 3394437..3395072(-) (vraR) [Bacillus subtilis strain NCIB 3610]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=184906 B4U62_RS17865 WP_003243201.1 3394437..3395072(-) (vraR) [Bacillus subtilis strain NCIB 3610]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408