Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A9E88_RS13330 Genome accession   NZ_CP015946
Coordinates   3006267..3006926 (-) Length   219 a.a.
NCBI ID   WP_025862552.1    Uniprot ID   -
Organism   Legionella pneumophila strain E1_P     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3001267..3011926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9E88_RS13315 (A9E88_13315) - 3002067..3002726 (+) 660 WP_010948343.1 hypothetical protein -
  A9E88_RS13320 (A9E88_13320) lcl 3002894..3004375 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  A9E88_RS13325 (A9E88_13325) uvrC 3004399..3006255 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  A9E88_RS13330 (A9E88_13330) letA 3006267..3006926 (-) 660 WP_025862552.1 two-component system response regulator LetA Regulator
  A9E88_RS13335 (A9E88_13335) phhA 3007051..3007869 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  A9E88_RS13340 (A9E88_13340) - 3008308..3009405 (+) 1098 WP_010948348.1 competence/damage-inducible protein A -
  A9E88_RS13345 (A9E88_13345) cgtA 3009364..3010389 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  A9E88_RS13350 (A9E88_13350) rpmA 3010604..3010882 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  A9E88_RS13355 (A9E88_13355) rplU 3010895..3011206 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24560.48 Da        Isoelectric Point: 5.1572

>NTDB_id=184404 A9E88_RS13330 WP_025862552.1 3006267..3006926(-) (letA) [Legionella pneumophila strain E1_P]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNTNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=184404 A9E88_RS13330 WP_025862552.1 3006267..3006926(-) (letA) [Legionella pneumophila strain E1_P]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACACAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.087

100

0.991
  letA Legionella pneumophila strain ERS1305867

99.087

100

0.991

Multiple sequence alignment