Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LLUC06_RS10100 Genome accession   NZ_CP015902
Coordinates   2020120..2020821 (-) Length   233 a.a.
NCBI ID   WP_081213670.1    Uniprot ID   A0A1V0P420
Organism   Lactococcus lactis subsp. lactis strain UC06     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015120..2025821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC06_RS10080 (LLUC06_1963) - 2015230..2016447 (-) 1218 WP_058220840.1 cysteine desulfurase -
  LLUC06_RS10085 (LLUC06_1964) sufD 2016447..2017703 (-) 1257 WP_021722250.1 Fe-S cluster assembly protein SufD -
  LLUC06_RS10090 (LLUC06_1965) sufC 2017841..2018611 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  LLUC06_RS10095 (LLUC06_1966) - 2018786..2020117 (-) 1332 WP_021722251.1 glycosyltransferase family 4 protein -
  LLUC06_RS10100 (LLUC06_1967) mecA 2020120..2020821 (-) 702 WP_081213670.1 adaptor protein MecA Regulator
  LLUC06_RS10105 (LLUC06_1968) - 2020951..2021685 (-) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  LLUC06_RS10110 (LLUC06_1969) - 2021685..2022371 (-) 687 WP_081213671.1 amino acid ABC transporter permease -
  LLUC06_RS10115 (LLUC06_1970) - 2022518..2023426 (-) 909 WP_039115860.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27058.41 Da        Isoelectric Point: 4.1244

>NTDB_id=183085 LLUC06_RS10100 WP_081213670.1 2020120..2020821(-) (mecA) [Lactococcus lactis subsp. lactis strain UC06]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYHYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=183085 LLUC06_RS10100 WP_081213670.1 2020120..2020821(-) (mecA) [Lactococcus lactis subsp. lactis strain UC06]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCATTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0P420

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.142

100

0.991
  mecA Lactococcus lactis subsp. cremoris KW2

96.567

100

0.966

Multiple sequence alignment