Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLJM3_RS08260 Genome accession   NZ_CP015901
Coordinates   1621208..1622680 (-) Length   490 a.a.
NCBI ID   WP_063284024.1    Uniprot ID   A0AA34TK64
Organism   Lactococcus cremoris strain JM3     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1616208..1627680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLJM3_RS08240 (LLJM3_1620) murG 1616524..1617597 (-) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  LLJM3_RS08245 (LLJM3_1621) murD 1617840..1619189 (-) 1350 WP_011676627.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLJM3_RS08250 (LLJM3_1622) - 1619358..1619699 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLJM3_RS08255 (LLJM3_1623) - 1619781..1621022 (-) 1242 WP_011676629.1 ammonium transporter -
  LLJM3_RS08260 (LLJM3_1624) covS 1621208..1622680 (-) 1473 WP_063284024.1 HAMP domain-containing histidine kinase Regulator
  LLJM3_RS08265 (LLJM3_1625) covR 1622686..1623378 (-) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLJM3_RS08270 (LLJM3_1626) - 1623535..1624065 (-) 531 WP_011676632.1 DUF177 domain-containing protein -
  LLJM3_RS08275 (LLJM3_1627) - 1624198..1624443 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLJM3_RS08280 (LLJM3_1628) - 1624767..1625129 (-) 363 WP_011676634.1 TIGR02328 family protein -
  LLJM3_RS08285 (LLJM3_1629) - 1625366..1626277 (-) 912 WP_011676635.1 CHAP domain-containing protein -
  LLJM3_RS08290 (LLJM3_1630) - 1626370..1627206 (-) 837 WP_011834858.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55871.70 Da        Isoelectric Point: 4.7005

>NTDB_id=183023 LLJM3_RS08260 WP_063284024.1 1621208..1622680(-) (covS) [Lactococcus cremoris strain JM3]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNHWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=183023 LLJM3_RS08260 WP_063284024.1 1621208..1622680(-) (covS) [Lactococcus cremoris strain JM3]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGATG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
ATTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTAGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTGCTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945

Multiple sequence alignment