Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLJM2_RS08315 Genome accession   NZ_CP015900
Coordinates   1619425..1620897 (-) Length   490 a.a.
NCBI ID   WP_081196783.1    Uniprot ID   -
Organism   Lactococcus cremoris strain JM2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1614425..1625897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLJM2_RS08295 (LLJM2_1626) murG 1614738..1615811 (-) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  LLJM2_RS08300 (LLJM2_1627) murD 1616054..1617403 (-) 1350 WP_081196782.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLJM2_RS08305 (LLJM2_1628) - 1617572..1617913 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLJM2_RS08310 (LLJM2_1629) - 1617998..1619239 (-) 1242 WP_015082643.1 ammonium transporter -
  LLJM2_RS08315 (LLJM2_1630) covS 1619425..1620897 (-) 1473 WP_081196783.1 HAMP domain-containing histidine kinase Regulator
  LLJM2_RS08320 (LLJM2_1631) covR 1620910..1621602 (-) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLJM2_RS08325 (LLJM2_1632) - 1621759..1622289 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLJM2_RS08330 (LLJM2_1633) - 1622422..1622667 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLJM2_RS08335 (LLJM2_1634) - 1622991..1623353 (-) 363 Protein_1617 TIGR02328 family protein -
  LLJM2_RS08340 (LLJM2_03305) - 1623590..1624501 (-) 912 Protein_1618 CHAP domain-containing protein -
  LLJM2_RS08345 (LLJM2_1637) - 1624594..1625430 (-) 837 WP_021165524.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55905.78 Da        Isoelectric Point: 4.7018

>NTDB_id=182975 LLJM2_RS08315 WP_081196783.1 1619425..1620897(-) (covS) [Lactococcus cremoris strain JM2]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=182975 LLJM2_RS08315 WP_081196783.1 1619425..1620897(-) (covS) [Lactococcus cremoris strain JM2]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAATCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.898

100

0.949

Multiple sequence alignment