Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   AT729_RS01940 Genome accession   NZ_CP015886
Coordinates   323197..324057 (-) Length   286 a.a.
NCBI ID   WP_002220276.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 38277     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 318197..329057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT729_RS01910 (AT729_00318) ispB 318683..319657 (+) 975 WP_002216396.1 octaprenyl diphosphate synthase -
  AT729_RS01915 (AT729_00319) - 319662..320108 (+) 447 WP_002220271.1 DUF441 domain-containing protein -
  AT729_RS01925 (AT729_00321) pilF 320600..322276 (+) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  AT729_RS01930 (AT729_00322) - 322361..322570 (-) 210 WP_002226032.1 DNA gyrase inhibitor YacG -
  AT729_RS01935 (AT729_00323) coaE 322563..323195 (-) 633 WP_002226034.1 dephospho-CoA kinase -
  AT729_RS01940 (AT729_00324) pilD 323197..324057 (-) 861 WP_002220276.1 prepilin peptidase Machinery gene
  AT729_RS01945 (AT729_00325) pilG 324131..325363 (-) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  AT729_RS01950 (AT729_00326) pgi 325873..327516 (+) 1644 WP_002235440.1 glucose-6-phosphate isomerase -
  AT729_RS01955 - 327486..327716 (+) 231 WP_079889348.1 hypothetical protein -
  AT729_RS01960 (AT729_00327) dapD 327726..328547 (+) 822 WP_079889349.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31359.40 Da        Isoelectric Point: 8.2213

>NTDB_id=182774 AT729_RS01940 WP_002220276.1 323197..324057(-) (pilD) [Neisseria meningitidis strain 38277]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=182774 AT729_RS01940 WP_002220276.1 323197..324057(-) (pilD) [Neisseria meningitidis strain 38277]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

96.14

99.65

0.958
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Vibrio campbellii strain DS40M4

44.928

96.503

0.434
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434

Multiple sequence alignment