Detailed information NTG0182767

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: AT729_RS00275
• Genome accession: NZ_CP015886
• Coordinates: 41723..42988 (+)
• Length: 421 a.a.
• NCBI ID: WP_002215249.1
• Uniprot ID: A0A425AK53
• Organism: Neisseria meningitidis strain 38277
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 36723..47988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT729_RS00250 (AT729_00043)	-	37454..38455 (+)	1002	WP_002238540.1	thiamine ABC transporter substrate-binding protein	-
AT729_RS00255 (AT729_00044)	-	38549..39397 (+)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
AT729_RS00260 (AT729_00045)	-	39423..39908 (+)	486	WP_002215245.1	CinA family protein	-
AT729_RS00265 (AT729_00046)	msrAB	40010..41578 (-)	1569	WP_002216163.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
AT729_RS00275 (AT729_00047)	pilA	41723..42988 (+)	1266	WP_002215249.1	signal recognition particle-docking protein FtsY	Machinery gene
AT729_RS13060	-	43465..43659 (-)	195	WP_025461142.1	hypothetical protein	-
AT729_RS00285 (AT729_00048)	pilC	43588..46728 (+)	3141	WP_079889315.1	PilC family type IV pilus tip adhesin	Machinery gene

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45185.50 Da
• Isoelectric Point: 4.5585

>NTDB_id=182767 AT729_RS00275 WP_002215249.1 41723..42988(+) (pilA) [Neisseria meningitidis strain 38277]
MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVESLTESVKGQVESAVETVSGAVEQVKEAVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=182767 AT729_RS00275 WP_002215249.1 41723..42988(+) (pilA) [Neisseria meningitidis strain 38277]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCCCGAGGAGGCTCAAGTTCAGGAAACTGCAGCAAA
AGCAGAATCCGAAGTTACTCAAATAGTTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAGCCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTAGAGAAACCGCTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCTGGCATCAACGGCGCGGGCAAAACCACATCCATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCACTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: A0A425AK53

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.062	100	0.941