Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   BZK07_RS10370 Genome accession   NZ_CP019593
Coordinates   2020776..2021483 (+) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain GD705     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015776..2026483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZK07_RS10315 (BZK07_10665) - 2016671..2016934 (-) 264 WP_001205732.1 hypothetical protein -
  BZK07_RS10320 (BZK07_10670) - 2016943..2017203 (-) 261 WP_000291506.1 DUF1108 family protein -
  BZK07_RS10325 (BZK07_10675) - 2017208..2017511 (-) 304 Protein_1926 DUF2482 family protein -
  BZK07_RS10330 (BZK07_10680) - 2017605..2017766 (-) 162 WP_031766022.1 DUF1270 domain-containing protein -
  BZK07_RS10335 (BZK07_10685) - 2017763..2018083 (-) 321 WP_001120197.1 DUF771 domain-containing protein -
  BZK07_RS10340 (BZK07_10690) - 2018138..2018518 (+) 381 WP_000762521.1 DUF2513 domain-containing protein -
  BZK07_RS10345 (BZK07_10695) - 2018505..2018702 (-) 198 WP_001148862.1 hypothetical protein -
  BZK07_RS10350 (BZK07_10700) - 2018718..2019473 (-) 756 WP_001148343.1 phage antirepressor KilAC domain-containing protein -
  BZK07_RS10355 (BZK07_10705) - 2019530..2020069 (+) 540 WP_000351243.1 hypothetical protein -
  BZK07_RS10360 (BZK07_10710) - 2020093..2020353 (-) 261 WP_000435341.1 transcriptional regulator -
  BZK07_RS10365 (BZK07_10715) - 2020366..2020605 (-) 240 WP_000548576.1 helix-turn-helix transcriptional regulator -
  BZK07_RS10370 (BZK07_10720) irvR 2020776..2021483 (+) 708 WP_000094093.1 XRE family transcriptional regulator Regulator
  BZK07_RS14410 - 2021495..2021641 (+) 147 WP_001049401.1 hypothetical protein -
  BZK07_RS10375 (BZK07_10725) - 2021638..2021823 (+) 186 WP_000100503.1 hypothetical protein -
  BZK07_RS10380 (BZK07_10730) - 2022023..2022190 (+) 168 WP_031806878.1 hypothetical protein -
  BZK07_RS10385 (BZK07_10735) - 2022330..2023034 (+) 705 WP_017804779.1 type II toxin-antitoxin system PemK/MazF family toxin -
  BZK07_RS10390 (BZK07_10740) - 2023227..2024264 (+) 1038 WP_084570131.1 site-specific integrase -
  BZK07_RS10395 (BZK07_10745) sph 2024315..2025145 (+) 831 Protein_1941 sphingomyelin phosphodiesterase -
  BZK07_RS10400 (BZK07_10750) - 2025407..2026423 (-) 1017 WP_000595612.1 leukocidin/hemolysin toxin family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=181433 BZK07_RS10370 WP_000094093.1 2020776..2021483(+) (irvR) [Staphylococcus aureus strain GD705]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=181433 BZK07_RS10370 WP_000094093.1 2020776..2021483(+) (irvR) [Staphylococcus aureus strain GD705]
ATGAGTTCATTTTCTTCGAATCTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTAAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTGTCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374

Multiple sequence alignment