Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   BWR56_RS02285 Genome accession   NZ_CP019562
Coordinates   486877..487554 (+) Length   225 a.a.
NCBI ID   WP_000548981.1    Uniprot ID   A0ABU5G1H8
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 481877..492554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS02270 (BWR56_0445) - 483935..485011 (-) 1077 WP_049505267.1 DUF2974 domain-containing protein -
  BWR56_RS02275 (BWR56_0446) - 485123..485899 (-) 777 WP_049505266.1 ferredoxin reductase -
  BWR56_RS02280 (BWR56_0447) - 485986..486555 (-) 570 WP_049505265.1 TetR/AcrR family transcriptional regulator -
  BWR56_RS02285 (BWR56_0448) braR 486877..487554 (+) 678 WP_000548981.1 response regulator transcription factor Regulator
  BWR56_RS02290 (BWR56_0449) - 487547..488521 (+) 975 WP_049505264.1 sensor histidine kinase -
  BWR56_RS10085 - 488528..488626 (+) 99 Protein_444 peptide ABC transporter -
  BWR56_RS02295 - 488682..488983 (+) 302 Protein_445 hypothetical protein -
  BWR56_RS02300 (BWR56_0450) - 489262..490311 (+) 1050 WP_049505263.1 DUF389 domain-containing protein -
  BWR56_RS02305 (BWR56_0451) thrS 490523..492466 (-) 1944 WP_049505262.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25863.98 Da        Isoelectric Point: 4.9898

>NTDB_id=180927 BWR56_RS02285 WP_000548981.1 486877..487554(+) (braR) [Streptococcus oralis strain S.MIT/ORALIS-351]
MHKILLVEDDQVIRQQVGKLLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGEVLSLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLAGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=180927 BWR56_RS02285 WP_000548981.1 486877..487554(+) (braR) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGCACAAGATTTTACTAGTAGAAGATGACCAAGTTATTCGGCAACAAGTGGGGAAACTGCTCTCTGAGTGGGGCTTTGA
GGTCGTTTTGGTAGAAGATTTTATGGAAGTATTGAGCCTTTTTGTTCAGTCAGAACCTCATTTGGTCCTCATGGATATTG
GTCTGCCTCTTTTTAATGGTTACCACTGGTGTCAGGAGATTCGTAAGATCTCTAAGGTGCCCATCATGTTTCTGTCTTCG
AGAGACCAGGCGATGGATATTGTCATGGCGATCAATATGGGGGCAGATGACTTTGTAACTAAGCCTTTTGACCAGCAGGT
CCTCCTTGCCAAGGTTCAGGGTCTGTTGCGCCGTTCCTATGAGTTTGGCCGTGATGAAAGTCTGCTAGAGTATGCGGGTG
TGATCCTCAATACCAAGTCTATGGACCTGCACTATCAGGGGGAAGTTCTGAGTTTGACCAAGAATGAATTTCAAATTTTG
CGAGTGCTGTTTGAACATGCTGGCAATATCGTGGCGCGTGATGACCTGATGCGGGAACTCTGGAATAGCGACTTTTTCAT
CGATGATAACACCTTGTCTGTAAACGTTGCTCGCTTGCGCAAAAAGTTGGAGGAGCAAGGTTTAGCAGGGTTTATCGAAA
CCAAGAAAGGGATAGGATACGGACTGAAACATGCTTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369