Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   A6M16_RS05255 Genome accession   NZ_CP015557
Coordinates   1046475..1047701 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain DN13     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041475..1052701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS05230 (A6M16_05235) - 1041814..1041996 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  A6M16_RS05235 (A6M16_05240) lepA 1042046..1043878 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  A6M16_RS05240 (A6M16_05245) - 1044104..1045360 (+) 1257 WP_063725262.1 ISL3 family transposase -
  A6M16_RS05245 (A6M16_05250) ndk 1045396..1045809 (-) 414 WP_063725263.1 nucleoside-diphosphate kinase -
  A6M16_RS05250 (A6M16_05255) yihA 1045832..1046419 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  A6M16_RS05255 (A6M16_05260) clpX 1046475..1047701 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  A6M16_RS05265 (A6M16_05270) - 1047899..1048411 (-) 513 WP_063725264.1 dihydrofolate reductase -
  A6M16_RS05270 (A6M16_05275) - 1048750..1049589 (-) 840 WP_063725265.1 thymidylate synthase -
  A6M16_RS05275 (A6M16_05280) - 1049642..1049944 (-) 303 WP_024396053.1 hypothetical protein -
  A6M16_RS05280 (A6M16_05285) - 1049956..1050234 (-) 279 WP_024381822.1 hypothetical protein -
  A6M16_RS05285 (A6M16_05290) - 1050360..1051319 (-) 960 WP_024396054.1 ROK family glucokinase -
  A6M16_RS05290 (A6M16_05295) - 1051440..1052696 (-) 1257 WP_063725266.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=180688 A6M16_RS05255 WP_002934974.1 1046475..1047701(-) (clpX) [Streptococcus suis strain DN13]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=180688 A6M16_RS05255 WP_002934974.1 1046475..1047701(-) (clpX) [Streptococcus suis strain DN13]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGCGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAACTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGCTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCCGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTTGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment