Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   A2I66_RS00215 Genome accession   NZ_CP015535
Coordinates   41018..42367 (-) Length   449 a.a.
NCBI ID   WP_065865881.1    Uniprot ID   -
Organism   Staphylococcus carnosus strain TMW 2.218     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 36018..47367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2I66_RS00180 - 36215..36427 (-) 213 WP_229347794.1 hypothetical protein -
  A2I66_RS00185 (A2I66_00175) - 36452..36991 (-) 540 WP_229347799.1 HTH domain-containing protein -
  A2I66_RS00190 (A2I66_00180) - 37161..37607 (-) 447 WP_065865876.1 JAB domain-containing protein -
  A2I66_RS00195 (A2I66_00185) - 37628..38134 (-) 507 WP_065865877.1 DUF1643 domain-containing protein -
  A2I66_RS00200 (A2I66_00190) - 38150..38461 (-) 312 WP_065865878.1 DUF960 family protein -
  A2I66_RS00205 (A2I66_00195) - 38557..38895 (-) 339 WP_065865879.1 SAUGI family uracil-DNA glycosylase inhibitor -
  A2I66_RS00210 (A2I66_00200) ccrB 39370..40998 (-) 1629 WP_065865880.1 recombinase family protein Machinery gene
  A2I66_RS00215 (A2I66_00205) ccrA 41018..42367 (-) 1350 WP_065865881.1 recombinase family protein Machinery gene
  A2I66_RS00220 (A2I66_00210) - 42538..42801 (-) 264 WP_065865882.1 hypothetical protein -
  A2I66_RS00225 (A2I66_00215) - 42867..44654 (-) 1788 WP_065865883.1 DUF927 domain-containing protein -
  A2I66_RS00230 (A2I66_00220) - 44654..44923 (-) 270 WP_031838353.1 hypothetical protein -
  A2I66_RS00235 (A2I66_00225) - 45078..46637 (-) 1560 WP_065865884.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52085.12 Da        Isoelectric Point: 10.1638

>NTDB_id=180494 A2I66_RS00215 WP_065865881.1 41018..42367(-) (ccrA) [Staphylococcus carnosus strain TMW 2.218]
MKQAIGYLRQSTLKQQSLSAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLIKLCQQYNVDILSVNDGYFDLNKSFDRLKLNIFISLAELESNNIGEQVSNGIKEKARQGKLITTHAPFGYHYY
KGTFVINPVEAQTVTAVFKYYLQGYGYKKIAQYLEKDNKLINRKPYQVRNIIMNPNYCGRVNNKYGTFDNMFPFIISKSV
YKDAQAIRVNKQVQRTPSANLLKQKIKCPCCDSTLTNMTIRKKEHTLRYYVCPKNMNESRFVCSFKGINAQELEVQVLAT
CQNFFQNQQLYSKINNTIHQRLKKQRVIEAKSMLTQEQLIDKLAKGMIDAETFRNQSQSVLQKRKIISSISDTQLQTSLQ
NVIQQSFTLNMLYPYIDEIRITKNKVLVGIYFKNEPLNIVNQTTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=180494 A2I66_RS00215 WP_065865881.1 41018..42367(-) (ccrA) [Staphylococcus carnosus strain TMW 2.218]
ATGAAACAAGCAATAGGTTATCTACGTCAAAGTACACTCAAACAACAATCACTCTCAGCCCAGAAACAAACCATCAAGGC
ATTAGCCGAAAAGCATAATATTCAACACATTACCTTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGTTATCGTCTGAATCGACTTCATCGTAAT
TTGAAAAATGCGCTAAAATTAATTAAATTATGCCAGCAGTACAATGTAGATATCTTGAGTGTTAACGATGGCTATTTTGA
CTTAAACAAATCATTTGATCGTCTAAAACTCAATATCTTCATTTCATTAGCTGAACTTGAGTCAAATAATATTGGTGAAC
AAGTAAGCAACGGGATAAAAGAAAAAGCACGTCAAGGTAAACTGATTACCACACATGCACCTTTTGGATATCATTATTAT
AAAGGCACATTTGTAATCAACCCAGTAGAAGCACAAACGGTGACTGCAGTATTCAAATACTATCTTCAAGGGTATGGTTA
CAAAAAGATTGCACAATATTTGGAAAAAGATAATAAGTTAATCAACCGAAAACCATATCAAGTACGTAACATTATTATGA
ACCCTAATTACTGTGGACGTGTGAATAACAAATACGGCACCTTTGATAATATGTTCCCATTTATTATCAGTAAATCAGTG
TATAAAGATGCTCAAGCAATACGAGTAAATAAACAAGTTCAGCGCACGCCTTCTGCTAATTTACTCAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACGCTGACAAATATGACGATAAGAAAAAAAGAACATACATTGCGCTATTATGTTTGTCCTA
AAAATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGGATAAATGCACAAGAATTAGAAGTTCAAGTCTTAGCAACA
TGTCAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATACGATTCATCAACGCCTCAAAAAACAAAGAGT
GATAGAAGCTAAAAGTATGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAAACATTCA
GGAATCAGTCTCAATCAGTGCTTCAAAAGCGCAAAATCATATCCTCAATAAGTGATACTCAGTTGCAAACGTCACTACAA
AATGTGATACAGCAAAGTTTCACGTTAAACATGCTGTATCCCTATATTGATGAAATTCGCATTACTAAAAACAAAGTCCT
TGTTGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCACGCAATCATCGATTGCCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(168-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(261-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

78.396

100

0.784
  ccrA Staphylococcus aureus N315

71.492

100

0.715

Multiple sequence alignment