Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A2I67_RS08245 Genome accession   NZ_CP015533
Coordinates   1603142..1603858 (+) Length   238 a.a.
NCBI ID   WP_046100375.1    Uniprot ID   -
Organism   Staphylococcus carnosus strain TMW 2.216     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1598142..1608858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2I67_RS08225 (A2I67_08050) - 1599399..1600199 (+) 801 WP_046100377.1 carbon-nitrogen family hydrolase -
  A2I67_RS13380 (A2I67_08055) - 1600512..1600592 (-) 81 WP_041612998.1 delta-lysin family phenol-soluble modulin -
  A2I67_RS08230 (A2I67_08060) - 1601090..1601536 (+) 447 WP_308669865.1 accessory gene regulator AgrB -
  A2I67_RS08235 (A2I67_08065) agrD 1601673..1601810 (+) 138 WP_015900791.1 cyclic lactone autoinducer peptide AgrD -
  A2I67_RS08240 (A2I67_08070) agrC 1601842..1603137 (+) 1296 WP_046100376.1 quorum-sensing sensor histidine kinase AgrC -
  A2I67_RS08245 (A2I67_08075) agrA 1603142..1603858 (+) 717 WP_046100375.1 quorum-sensing response regulator AgrA Regulator
  A2I67_RS08250 (A2I67_08080) - 1603905..1605377 (-) 1473 WP_115359453.1 GH32 C-terminal domain-containing protein -
  A2I67_RS08255 (A2I67_08085) - 1605589..1606674 (+) 1086 WP_046100373.1 YeeE/YedE family protein -
  A2I67_RS08260 (A2I67_08090) - 1606701..1606925 (+) 225 WP_046100372.1 sulfurtransferase TusA family protein -
  A2I67_RS08265 (A2I67_08095) - 1606975..1607619 (-) 645 WP_046100371.1 redox-sensing transcriptional repressor Rex -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27873.74 Da        Isoelectric Point: 4.9636

>NTDB_id=180476 A2I67_RS08245 WP_046100375.1 1603142..1603858(+) (agrA) [Staphylococcus carnosus strain TMW 2.216]
MKIIICEDDQQQRAHIEEIINNYIMIEEKPLEIALSTNDPYEVIEYAKNTNDICCYFLDIQLDADINGIKLGSELRKFDT
VGNIVFVTSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESNVETIELKRGSNSVYVNYDDVM
FFESSTKSHRLIAHLDNRQIEFYGSLKELSNIDERFFRCHKSFVINRNNIEEVISKEREIHFKNGEHCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=180476 A2I67_RS08245 WP_046100375.1 1603142..1603858(+) (agrA) [Staphylococcus carnosus strain TMW 2.216]
ATGAAAATTATTATTTGTGAAGACGACCAGCAACAACGCGCACATATCGAAGAAATTATCAATAACTATATAATGATTGA
AGAAAAGCCATTAGAAATTGCTCTCTCAACTAATGATCCATATGAAGTAATTGAATACGCTAAAAATACAAATGACATTT
GTTGTTACTTCTTAGATATTCAACTTGACGCAGATATAAATGGGATTAAACTCGGTAGTGAGTTACGTAAATTTGATACG
GTTGGGAATATTGTTTTTGTGACAAGTCATAGCGAATTGACTTACTTAACTTTTGTTTATAAAGTAGCAGCAATGGATTT
TATCTTTAAAGATGATCCTAGCGAAATGAAATCACGGATTATTGATTGCATTGAAACAGCACTTACACGTTTGCAGCTAT
TATCTAAAGAAAGCAACGTTGAAACAATCGAACTTAAAAGAGGCAGTAATTCTGTCTATGTTAATTACGATGATGTAATG
TTTTTCGAATCATCCACTAAATCTCATAGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGAAGTTTGAA
AGAACTCAGTAATATTGATGAACGCTTCTTCCGTTGTCACAAAAGCTTTGTAATCAACCGCAATAATATCGAAGAAGTGA
TTTCAAAAGAACGTGAAATTCACTTTAAAAACGGCGAACATTGCTATGTCTCTGTCCGTAACCTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

78.992

100

0.79
  comE Streptococcus mitis NCTC 12261

34.263

100

0.361

Multiple sequence alignment