Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BWQ98_RS01855 Genome accession   NZ_CP019299
Coordinates   341662..342294 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HKU1-14     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 336662..347294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWQ98_RS01830 (BWQ98_01830) mvaD 336939..337892 (+) 954 WP_000373460.1 diphosphomevalonate decarboxylase -
  BWQ98_RS01835 (BWQ98_01835) - 337879..338886 (+) 1008 WP_050233392.1 phosphomevalonate kinase -
  BWQ98_RS01840 (BWQ98_01840) fni 338870..339880 (+) 1011 WP_000210610.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  BWQ98_RS01845 (BWQ98_01845) liaF 339958..340656 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  BWQ98_RS01850 (BWQ98_01850) - 340653..341648 (+) 996 WP_000743662.1 sensor histidine kinase -
  BWQ98_RS01855 (BWQ98_01855) vraR 341662..342294 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  BWQ98_RS11670 (BWQ98_01860) - 342295..342537 (+) 243 Protein_344 DNA alkylation repair protein -
  BWQ98_RS11370 - 342462..343064 (+) 603 Protein_345 DNA alkylation repair protein -
  BWQ98_RS01875 (BWQ98_01875) - 343523..344125 (+) 603 Protein_346 serine protease -
  BWQ98_RS01880 (BWQ98_01880) - 344427..344786 (+) 360 WP_000378123.1 tyrosine-type recombinase/integrase -
  BWQ98_RS01885 (BWQ98_01885) tig 344980..346263 (+) 1284 WP_000116462.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=179898 BWQ98_RS01855 WP_000698433.1 341662..342294(+) (vraR) [Streptococcus pneumoniae strain HKU1-14]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=179898 BWQ98_RS01855 WP_000698433.1 341662..342294(+) (vraR) [Streptococcus pneumoniae strain HKU1-14]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41