Detailed information NTG0178520

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: A5478_RS09490
• Genome accession: NZ_CP015342
• Coordinates: 2116013..2118745 (+)
• Length: 910 a.a.
• NCBI ID: WP_027225145.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain D-7632
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2111013..2123745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A5478_RS09470 (A5478_09470)	gstA	2111156..2111761 (-)	606	WP_027225142.1	glutathione transferase GstA	-
A5478_RS09475 (A5478_09475)	-	2111958..2112953 (-)	996	WP_027225143.1	hypothetical protein	-
A5478_RS09480 (A5478_09480)	-	2112994..2114256 (-)	1263	WP_027225144.1	serine hydrolase domain-containing protein	-
A5478_RS09485 (A5478_09485)	gltX	2114502..2115914 (-)	1413	WP_011946808.1	glutamate--tRNA ligase	-
A5478_RS09490 (A5478_09490)	letS	2116013..2118745 (+)	2733	WP_027225145.1	two-component system sensor histidine kinase LetS	Regulator
A5478_RS09495 (A5478_09495)	-	2118842..2120086 (+)	1245	WP_027225146.1	6-phosphofructokinase	-
A5478_RS09500 (A5478_09500)	pilA2	2120083..2120496 (-)	414	WP_027225147.1	pilin	Machinery gene
A5478_RS09505 (A5478_09505)	pilA2	2120689..2121099 (-)	411	WP_011214168.1	pilin	Machinery gene
A5478_RS09510 (A5478_09510)	-	2121402..2121719 (+)	318	WP_027225148.1	BolA family protein	-
A5478_RS09515 (A5478_09515)	-	2121794..2123215 (+)	1422	WP_027225149.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103061.57 Da
• Isoelectric Point: 7.5330

>NTDB_id=178520 A5478_RS09490 WP_027225145.1 2116013..2118745(+) (letS) [Legionella pneumophila strain D-7632]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKELSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISQEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRILTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSSDLSSIDMKKSGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIELMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
ANADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=178520 A5478_RS09490 WP_027225145.1 2116013..2118745(+) (letS) [Legionella pneumophila strain D-7632]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGCAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCG
GAGGTAAAAGCTTTGGCATTTTATAATGCTGATGGTCGATTAATTGCTTATCGTGGTGGCAAGCATTCTATTCATAAACC
ATTCAACCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAACCCATTCACCATTAATTTTATAGCACCAA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAGTTCAAAGAGCTTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCTATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACCCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGTAATGAATTTGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCACCACATTGAAATCGCCAC
AGCAGATCTGCAACAAAGTCTAGAACTTCTGGAAGAAAAAAACATTGAGCTATCACTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGCCATGAAATTCGCACCCCAATGAATGGCGTGATTGGTTTTACA
AACGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACATAA
GAGGTTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACAAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCGGGATTAGGCTTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGACGTATTAGTCT
AACCAGTGAAATCAACAAAGGCTCTACTTTTAGCGCGCGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATAGGTAATGGC
TTGGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAATATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAATCAAGGATGTGAGCGACAAGCTGCTGAACTCATTGCCAAACATAAGCAAATCCCTT
TCGTGTTAATTTCCAAATGGCCTATTAATGATTTTGCAGCGCTTGGTGCCAGGGGTTTTCTTTACAAACCTATTAGTATC
CAAAAGCTTCAGGATCTGATTGAATCGATAGCCAATGAAAACCAAACCGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGCGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACCACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTTGATCTGCATATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGTCAAAAATCCCTAATGAA
TAAACACTCCCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATCTGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAACAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATCGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTCATAGAAGA
ATTATATAAGAATCGTGAAGAGTTTATTGAGTTAATGCATCAAAAAAACGTAAAGGGCCTGGCTGATTTGGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGTGTACCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAAGCTTGCAAGACGAACA
GCTAATGCTGATAATTTAACCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTATTCACAATAA

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (819-899)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Response regulator receiver domain (Response_reg) (678-787)

• Single cache domain 4 (sCache_4) (36-180)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.67	100	0.997