Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   A5478_RS05960 Genome accession   NZ_CP015342
Coordinates   1321412..1322740 (+) Length   442 a.a.
NCBI ID   WP_027224131.1    Uniprot ID   -
Organism   Legionella pneumophila strain D-7632     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1316412..1327740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5478_RS05940 (A5478_05940) amrS 1316542..1317618 (+) 1077 WP_013101417.1 AmmeMemoRadiSam system radical SAM enzyme -
  A5478_RS05945 (A5478_05945) - 1317677..1318096 (+) 420 WP_011213527.1 lpg1171 family Dot/Icm T4SS effector -
  A5478_RS05950 (A5478_05950) lidL 1318246..1319730 (+) 1485 WP_072363922.1 Dot/Icm type IV secretion system effector LidL -
  A5478_RS05955 (A5478_05955) - 1319829..1321415 (+) 1587 WP_027224132.1 sensor histidine kinase -
  A5478_RS05960 (A5478_05960) pilR 1321412..1322740 (+) 1329 WP_027224131.1 sigma-54-dependent transcriptional regulator Regulator
  A5478_RS05965 (A5478_05965) - 1323170..1323415 (+) 246 WP_011213531.1 hypothetical protein -
  A5478_RS05970 (A5478_05970) - 1323853..1324788 (-) 936 WP_027224130.1 alpha/beta fold hydrolase -
  A5478_RS05975 (A5478_05975) - 1325067..1326503 (-) 1437 WP_027224129.1 M48 family metalloprotease -
  A5478_RS05980 (A5478_05980) ribD 1326566..1327639 (+) 1074 WP_027224128.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49244.26 Da        Isoelectric Point: 7.1405

>NTDB_id=178508 A5478_RS05960 WP_027224131.1 1321412..1322740(+) (pilR) [Legionella pneumophila strain D-7632]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQMPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKLDEGLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGSFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=178508 A5478_RS05960 WP_027224131.1 1321412..1322740(+) (pilR) [Legionella pneumophila strain D-7632]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAATTATTAACTCTTACTTTATCACGTATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATAGAAATTGTAAAATTCATTCAGAAATACAAACCGCAGATGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCTTGATGAAGGTCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCAGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGCTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCTATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCAGCTCATGGTGGTACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTTAAATTGCTACGTGCCATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAGAATTTGATTGAGGAAGTTAATGCAGGGTCGTTTCGTCAAGATTTATATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAATTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAGCTGGAGAATATCCTCGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCCAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.193

100

0.597
  pilR Acinetobacter baumannii strain A118

48.584

100

0.505

Multiple sequence alignment