Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V471_RS10035 Genome accession   NZ_CP015283
Coordinates   2125619..2126845 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain ATCC 25975     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2120619..2131845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS10005 (V471_09835) plsY 2120964..2121605 (+) 642 WP_014633423.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  V471_RS10010 (V471_09840) - 2121723..2122100 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  V471_RS10015 (V471_09845) - 2122175..2122429 (-) 255 WP_002886199.1 DUF1912 family protein -
  V471_RS10020 (V471_09850) mmuM 2122542..2123492 (-) 951 WP_049553995.1 homocysteine S-methyltransferase -
  V471_RS10025 (V471_09855) - 2123504..2124880 (-) 1377 WP_049553996.1 amino acid permease -
  V471_RS10030 (V471_09860) yihA 2125010..2125609 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V471_RS10035 (V471_09865) clpX 2125619..2126845 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  V471_RS10995 - 2126863..2127033 (-) 171 WP_002886174.1 hypothetical protein -
  V471_RS10040 (V471_09870) - 2127038..2127541 (-) 504 WP_045001870.1 dihydrofolate reductase -
  V471_RS10045 (V471_09875) - 2127650..2128510 (-) 861 WP_014633426.1 thymidylate synthase -
  V471_RS10050 (V471_09880) - 2128816..2129982 (+) 1167 WP_014633427.1 hydroxymethylglutaryl-CoA synthase -
  V471_RS10055 (V471_09885) - 2129984..2131255 (+) 1272 WP_084871476.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=178327 V471_RS10035 WP_002890340.1 2125619..2126845(-) (clpX) [Streptococcus salivarius strain ATCC 25975]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=178327 V471_RS10035 WP_002890340.1 2125619..2126845(-) (clpX) [Streptococcus salivarius strain ATCC 25975]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATTGC
CGGCAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAATTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTTGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACTGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGCATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACAAAGAAT
ATTCTTTTTATCGTAGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATCCAAAAATTCGGTC
TTATCCCCGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTGGATGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACTAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment