Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   V471_RS04615 Genome accession   NZ_CP015283
Coordinates   886044..887363 (+) Length   439 a.a.
NCBI ID   WP_084871141.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 881044..892363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS04590 (V471_04525) - 881888..882652 (+) 765 WP_045771733.1 ABC transporter ATP-binding protein -
  V471_RS04595 (V471_04530) - 882652..883362 (+) 711 WP_013990087.1 ABC transporter ATP-binding protein -
  V471_RS04600 (V471_04535) - 883497..884156 (+) 660 WP_070849374.1 CBS and ACT domain-containing protein -
  V471_RS04605 (V471_04540) cysK 884335..885261 (-) 927 WP_070849377.1 cysteine synthase A -
  V471_RS04610 (V471_04545) - 885363..885989 (-) 627 WP_070849380.1 YigZ family protein -
  V471_RS04615 (V471_04550) comFA/cflA 886044..887363 (+) 1320 WP_084871141.1 DEAD/DEAH box helicase Machinery gene
  V471_RS04620 (V471_04555) - 887344..888006 (+) 663 WP_045001926.1 ComF family protein -
  V471_RS04625 (V471_04560) hpf 888085..888633 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50682.86 Da        Isoelectric Point: 9.2418

>NTDB_id=178299 V471_RS04615 WP_084871141.1 886044..887363(+) (comFA/cflA) [Streptococcus salivarius strain ATCC 25975]
MVPKEYYGRLFTKEQLLVDYHSEALTLESMIKVDKQLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFLSK
TSEIEFPVLKWLGALTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLENKGRVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPIVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGSLEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLVYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSTVVEKFREKELSVLVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=178299 V471_RS04615 WP_084871141.1 886044..887363(+) (comFA/cflA) [Streptococcus salivarius strain ATCC 25975]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGCTAGTGGACTATCACTCAGAGGCTTTGACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTATAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGTAGAAATCAAGAAGGGAAAGAACTTTATTATTTTCTTTCAAAA
ACATCAGAAATTGAGTTTCCTGTTTTGAAGTGGTTAGGAGCACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACACGCTGTGACTGGTGCTGGTAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAATAAAGGTCGTGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTGTTTCTACGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGATTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAAGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGTTATATTTATTTAACAGCAACTTCTACA
TTATCTTTAGAGGAGCAGGTGCGACTTGGATCTTTAGAAAAGCATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTGTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTTACTAGCATT
CTGCAAAAATATCTTCCAGACGAAAAAATGGCCTTTGTTTCCTCAAAAAGTGAGGAGCGTTCAACTGTCGTAGAGAAGTT
CCGAGAAAAAGAACTATCCGTCTTAGTGACAACAACTATCCTCGAACGTGGTGTGACCTTTCCACAAGTAGATGTTTTTG
TTTGCATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(95-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae D39

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae R6

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae TIGR4

55.684

98.178

0.547
  comFA/cflA Streptococcus mitis NCTC 12261

54.839

98.861

0.542
  comFA/cflA Streptococcus mitis SK321

54.292

98.178

0.533
  comFA Lactococcus lactis subsp. cremoris KW2

45.564

94.989

0.433
  comFA Latilactobacillus sakei subsp. sakei 23K

37.615

99.317

0.374

Multiple sequence alignment