Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NX99_RS06875 Genome accession   NZ_CP015282
Coordinates   1517647..1518882 (-) Length   411 a.a.
NCBI ID   WP_002892211.1    Uniprot ID   J7SI15
Organism   Streptococcus salivarius strain ATCC 27945     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1512647..1523882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS06855 (NX99_06725) - 1513676..1513867 (-) 192 WP_037599384.1 DUF951 domain-containing protein -
  NX99_RS06860 (NX99_06730) dnaN 1513919..1515055 (-) 1137 WP_084915168.1 DNA polymerase III subunit beta -
  NX99_RS06865 (NX99_06735) dnaA 1515211..1516575 (-) 1365 WP_037599382.1 chromosomal replication initiator protein DnaA -
  NX99_RS06870 (NX99_06740) spo0J 1516814..1517581 (-) 768 WP_084915170.1 ParB/RepB/Spo0J family partition protein Regulator
  NX99_RS06875 (NX99_06745) htrA 1517647..1518882 (-) 1236 WP_002892211.1 S1C family serine protease Regulator
  NX99_RS06880 (NX99_06750) rlmH 1519088..1519567 (+) 480 WP_037598563.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  NX99_RS06885 (NX99_06755) - 1519584..1520267 (+) 684 WP_002892206.1 YoaK family protein -
  NX99_RS06905 (NX99_06775) - 1520819..1523413 (-) 2595 WP_084915172.1 YfhO family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42959.14 Da        Isoelectric Point: 4.6304

>NTDB_id=178231 NX99_RS06875 WP_002892211.1 1517647..1518882(-) (htrA) [Streptococcus salivarius strain ATCC 27945]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=178231 NX99_RS06875 WP_002892211.1 1517647..1518882(-) (htrA) [Streptococcus salivarius strain ATCC 27945]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTACTAGGTGGTCTACTAGGTGC
CTTTATCCTATTAACAGCAGCAGGGGTATCTTTTACCAATACAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ACAATACAACAGATACAACTAAGGCCGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGCTCA
TCTTCAGATTCCCTAAATGAACTTTATGGTCGTATTTTTGGTGGAGATGATAGTTCTGATTCTAGCCAAGACAAATCAAA
AGATTCTGATGGATTGCAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAAGATGGGAAAGAGGCCTACATCGTAA
CCAACAACCACGTTGTTGATGGTGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATAAAAACCGTCGCAGAATTTGCAGATTC
AAACTCCCTCACAGTTGGTGAAAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTATCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTCTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCTGGTGGTGCCTTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
GATTTCATCAACGTCAGCAGTCGCTGGTAGTGCCGTTGAAGGTATGGGATTCGCCATTCCATCAAACGATGTTGTCGAAA
TCATTAATCAATTGGAAAAAGACGGTAAAGTTACACGCCCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGAAGTTAAATCTGGAGTTGTTGTCGGTAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATTACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTATCTGACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(118-263)

Peptidase family M50 (Peptidase_M50)

(4-406)

PDZ domain (PDZ_2)

(307-402)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SI15

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.787

98.054

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.524

100

0.577
  htrA Streptococcus mitis NCTC 12261

54.768

99.513

0.545
  htrA Streptococcus pneumoniae TIGR4

54.523

99.513

0.543
  htrA Streptococcus pneumoniae D39

54.523

99.513

0.543
  htrA Streptococcus pneumoniae Rx1

54.523

99.513

0.543
  htrA Streptococcus pneumoniae R6

54.523

99.513

0.543

Multiple sequence alignment