Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NX99_RS05195 Genome accession   NZ_CP015282
Coordinates   1194835..1196154 (-) Length   439 a.a.
NCBI ID   WP_084915017.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1184590..1196154 1194835..1196154 within 0


Gene organization within MGE regions


Location: 1184590..1196154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS05115 (NX99_05030) recX 1184590..1185366 (+) 777 WP_084915013.1 recombination regulator RecX -
  NX99_RS05120 (NX99_05035) - 1185437..1185970 (+) 534 WP_002886644.1 DUF402 domain-containing protein -
  NX99_RS05125 (NX99_05040) - 1186000..1186659 (-) 660 WP_084915015.1 DUF1803 domain-containing protein -
  NX99_RS05130 (NX99_05045) - 1186714..1187646 (-) 933 WP_014633932.1 manganese-dependent inorganic pyrophosphatase -
  NX99_RS05185 (NX99_05100) hpf 1193565..1194113 (-) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  NX99_RS05190 (NX99_05105) - 1194192..1194854 (-) 663 WP_002883740.1 ComF family protein -
  NX99_RS05195 (NX99_05110) comFA/cflA 1194835..1196154 (-) 1320 WP_084915017.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50617.55 Da        Isoelectric Point: 8.9972

>NTDB_id=178214 NX99_RS05195 WP_084915017.1 1194835..1196154(-) (comFA/cflA) [Streptococcus salivarius strain ATCC 27945]
MVPKEYYGRLFTKEQLPVDYHSGAFTLESMIKVDKQLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGNELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGSLEKHHLARRFHGNPLVLPKFFWQGRLQKSLMRGKLPRPLVYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=178214 NX99_RS05195 WP_084915017.1 1194835..1196154(-) (comFA/cflA) [Streptococcus salivarius strain ATCC 27945]
ATGGTACCTAAAGAATATTATGGACGGCTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGGGGCATTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGTAGAAATCAAGAAGGAAATGAACTCTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGTTTTGAAGTGGTTGGGGGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACCGGTGCTGGTAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGATCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTTTTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTGTTTATCAGA
TTAAAAAGCAACGTAAATCCAAATTCCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTTACTAGCATT
CTGCAAAAATATCTTCCAGACGAAAAAATGGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGGGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACGGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGTTGTCGAGAAGAAATAAAGGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae D39

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae R6

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae TIGR4

56.381

98.178

0.554
  comFA/cflA Streptococcus mitis NCTC 12261

55.53

98.861

0.549
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.844

99.317

0.376

Multiple sequence alignment