Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NX99_RS04105 Genome accession   NZ_CP015282
Coordinates   967504..968730 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain ATCC 27945     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 962504..973730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS04075 (NX99_04000) plsY 962845..963486 (+) 642 WP_084914847.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  NX99_RS04080 (NX99_04005) - 963608..963985 (-) 378 WP_084914848.1 helix-hairpin-helix domain-containing protein -
  NX99_RS04085 (NX99_04010) - 964060..964314 (-) 255 WP_002886199.1 DUF1912 family protein -
  NX99_RS04090 (NX99_04015) mmuM 964427..965377 (-) 951 WP_002885890.1 homocysteine S-methyltransferase -
  NX99_RS04095 (NX99_04020) - 965389..966765 (-) 1377 WP_080610350.1 amino acid permease -
  NX99_RS04100 (NX99_04025) yihA 966895..967494 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NX99_RS04105 (NX99_04030) clpX 967504..968730 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NX99_RS09870 - 968748..968918 (-) 171 WP_002886174.1 hypothetical protein -
  NX99_RS04110 (NX99_04035) - 968923..969426 (-) 504 WP_002885904.1 dihydrofolate reductase -
  NX99_RS04115 (NX99_04040) - 969535..970395 (-) 861 WP_084914850.1 thymidylate synthase -
  NX99_RS04120 (NX99_04045) - 970866..972032 (+) 1167 WP_038675548.1 hydroxymethylglutaryl-CoA synthase -
  NX99_RS04125 (NX99_04050) - 972034..973305 (+) 1272 WP_013990948.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=178207 NX99_RS04105 WP_002890340.1 967504..968730(-) (clpX) [Streptococcus salivarius strain ATCC 27945]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=178207 NX99_RS04105 WP_002890340.1 967504..968730(-) (clpX) [Streptococcus salivarius strain ATCC 27945]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCGAATATTCTCATGATTGGACCAACCGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGAAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCTGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGGATTATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGATGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCTCTAGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCACGTGGGCTTCGCTCTATCATTGAGGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAAGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment