Detailed information NTG0177447

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: A4H00_RS06475
• Genome accession: NZ_CP015196
• Coordinates: 1262367..1264580 (-)
• Length: 737 a.a.
• NCBI ID: WP_067088344.1
• Uniprot ID: -
• Organism: Streptococcus marmotae strain HTS5
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1257367..1269580

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4H00_RS06455	-	1258070..1258507 (+)	438	WP_067088336.1	GNAT family N-acetyltransferase	-
A4H00_RS06460	ileS	1258518..1261316 (+)	2799	WP_067088338.1	isoleucine--tRNA ligase	-
A4H00_RS06465	-	1261495..1261797 (-)	303	WP_067088340.1	DUF1827 family protein	-
A4H00_RS06470	-	1261858..1262310 (-)	453	WP_067088342.1	NUDIX hydrolase	-
A4H00_RS06475	clpE	1262367..1264580 (-)	2214	WP_067088344.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
A4H00_RS06480	-	1264853..1265083 (+)	231	WP_067088346.1	DUF1797 family protein	-
A4H00_RS06485	-	1265206..1265895 (+)	690	WP_067088348.1	amino acid ABC transporter permease	-
A4H00_RS06490	-	1265888..1266622 (+)	735	WP_067088350.1	amino acid ABC transporter ATP-binding protein	-
A4H00_RS06495	-	1267013..1267864 (+)	852	WP_067088351.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
A4H00_RS06500	-	1267876..1268736 (+)	861	WP_067088353.1	NAD(P)H-hydrate dehydratase	-

Sequence

Protein

• Length: 737 a.a.
• Molecular weight: 81698.99 Da
• Isoelectric Point: 5.2690

>NTDB_id=177447 A4H00_RS06475 WP_067088344.1 1262367..1264580(-) (clpE) [Streptococcus marmotae strain HTS5]
MLCHNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILKGLGDLTNPNNMDPFSEFFNNIGGIPGHTPAGKSR
NQTPPTQAGGGNRGNSGGSTPPKQPNGLLEEFGINVTEIARRGDIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGK
TAVVEGLAQKIVDGDVPQKLQGREVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKEIILFIDEIHEIVGAGSAGDGN
MDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILKGIQSKYQDYHHVKYTDEAIEAA
AILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKAQATRDEDFEKAAYFRDQIAKYKEMQKAT
ISEEDIPVITEKEIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFL
FVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEIEKA
HPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFSPEFMNRFDGII
EFHALSKENLLHIVDLMLLDVNQRLATTGLTLHVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDALTDFYLEHPEEKN
LRAVLTSKGDIAIKAKS

Nucleotide

• Length: 2214 bp

>NTDB_id=177447 A4H00_RS06475 WP_067088344.1 1262367..1264580(-) (clpE) [Streptococcus marmotae strain HTS5]
ATGCTTTGTCATAACTGTAATATTAATGATGCAACCATTCATCTTTATACAAATCTAAATGGAAAACAACAACAAGTGGA
TCTCTGCCACAACTGTTACCAAATCATGAAAACTGATCCAAATAATGCCATTTTAAAAGGCTTAGGCGATTTAACAAATC
CAAATAATATGGATCCCTTTAGCGAATTCTTCAATAATATCGGAGGCATTCCTGGACACACACCAGCTGGAAAGAGCCGC
AATCAAACACCGCCAACCCAAGCAGGCGGTGGCAATCGTGGCAACAGCGGTGGATCAACTCCGCCAAAACAACCAAACGG
CCTCCTAGAAGAATTTGGGATCAATGTCACTGAAATTGCTCGCCGTGGGGATATTGACCCCGTTATCGGTCGAGATGAAG
AGATCAAGCGTGTCATTGAAATTCTTAACCGTAGGACCAAGAATAACCCTGTCCTAATCGGAGAACCTGGAGTCGGAAAA
ACAGCCGTTGTTGAAGGTCTAGCTCAAAAAATCGTTGACGGAGATGTCCCACAAAAACTCCAAGGACGAGAAGTCATTCG
ACTCGATGTGGTTAGCCTCGTTCAAGGAACGGGTATCCGTGGGCAATTTGAAGAACGCATGCAAAAGCTCATGGAAGAAA
TCCGCAACCGTAAGGAAATCATTCTCTTTATCGATGAAATCCATGAAATCGTCGGTGCTGGTTCTGCCGGTGACGGTAAC
ATGGATGCTGGAAATATCCTAAAACCTGCCCTTGCTCGTGGAGAAATGCAGCTAGTCGGCGCAACAACGCTCAACGAATA
CCGCATTATCGAAAAAGATGCCGCTTTGGAACGTCGTATGCAGCCTGTTAAGGTTGATGAGCCAAGTGTGGACGAGACCA
TTACCATTCTAAAAGGGATCCAAAGCAAGTACCAAGACTATCATCATGTTAAATACACCGATGAAGCTATTGAAGCGGCT
GCCATTTTGTCCAACCGCTACATTCAAGACCGCTTCTTGCCTGATAAAGCTATTGACTTACTCGATGAGGCAGGTTCAAA
GATGAACTTGACGCTGAATTTCGTTGATCCAAAAGAAATTGATCAGCGCTTGATTGATGCTGAAAATCGCAAGGCCCAGG
CCACCCGTGATGAGGATTTTGAAAAGGCCGCCTACTTCCGCGACCAGATTGCCAAATACAAAGAGATGCAAAAAGCGACA
ATCAGCGAGGAAGATATCCCTGTCATTACCGAAAAAGAAATCGAAGCCATCATTGAGCAAAAAACCAATATTCCAGTCGG
TGATTTGAAAGAAAAAGAACAGTCGCAATTAGTCAATCTTGCAAATGACCTCAAGGCACACGTTATCGGTCAAGACGATG
CCGTTGATAAAATTGCCAAAGCTATTCGCCGCAATCGGGTAGGACTCGGTGCACCAAACCGTCCAATTGGAAGTTTCCTT
TTCGTTGGACCAACAGGGGTCGGAAAAACCGAGCTATCCAAACAACTCGCCATCGAACTCTTTGGTTCTGCCGATAGTAT
GATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTGTCGCAAAATTGGTCGGGGCTCCTCCAGGCTATGTCGGCT
ACGAAGAAGCAGGACAATTAACCGAAAAAGTCCGTCGCAATCCTTACTCGCTCATTCTTCTTGATGAGATTGAAAAAGCC
CACCCTGATGTCATGCACATGTTCCTTCAAGTCCTTGACGACGGTCGCTTGACAGATGGCCAAGGCCGCACAGTTAGCTT
CAAGGATACCATCATCATCATGACCTCCAATGCCGGAACAGGTAAGGTCGAAGCAAGTGTTGGCTTTGGTGCTGCGATGG
AAGGTCGTACCCAGTCTGTTCTCGGTCAATTGAGCAATTTCTTTAGCCCAGAATTTATGAACCGCTTTGACGGCATTATT
GAATTCCATGCCCTTAGCAAGGAAAATCTCCTTCATATCGTGGATCTCATGCTCCTTGATGTTAATCAGCGCCTAGCAAC
AACTGGACTCACACTCCATGTGACCGACAAGGTCAAGGAAAAATTGGTGGACTTGGGCTACGATCCAAAAATGGGAGCCC
GTCCGCTTCGTAGAACCATTCAAGAACACATCGAAGATGCACTGACCGACTTCTACTTGGAACATCCAGAAGAAAAGAAT
TTACGAGCAGTCCTTACTAGCAAGGGGGATATTGCCATAAAGGCAAAATCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (645-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (151-270)

• AAA lid domain (AAA_lid_9) (289-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (474-637)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.591	100	0.83
clpE	Streptococcus pneumoniae D39	82.591	100	0.83
clpE	Streptococcus pneumoniae R6	82.591	100	0.83
clpE	Streptococcus pneumoniae TIGR4	82.591	100	0.83
clpE	Streptococcus mutans UA159	82.013	100	0.829
clpC	Lactococcus lactis subsp. cremoris KW2	79.201	98.507	0.78
clpC	Bacillus subtilis subsp. subtilis str. 168	51.565	91.045	0.469
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.827	89.417	0.41
clpC	Streptococcus thermophilus LMD-9	47.847	85.075	0.407
clpC	Streptococcus pneumoniae Rx1	48	84.803	0.407
clpC	Streptococcus pneumoniae D39	48	84.803	0.407
clpC	Streptococcus mutans UA159	48.154	84.532	0.407
clpC	Streptococcus pneumoniae TIGR4	47.84	84.803	0.406
clpC	Streptococcus thermophilus LMG 18311	47.528	85.075	0.404