Detailed information NTG0177432

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A4H00_RS03900
• Genome accession: NZ_CP015196
• Coordinates: 780998..782191 (+)
• Length: 397 a.a.
• NCBI ID: WP_067087516.1
• Uniprot ID: -
• Organism: Streptococcus marmotae strain HTS5
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 775998..787191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4H00_RS03870	-	778073..779059 (+)	987	WP_067087512.1	IS30 family transposase	-
A4H00_RS03890	-	779621..780154 (-)	534	WP_237334214.1	YoaK family protein	-
A4H00_RS03895	rlmH	780180..780659 (-)	480	WP_067087514.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A4H00_RS03900	htrA	780998..782191 (+)	1194	WP_067087516.1	S1C family serine protease	Regulator
A4H00_RS03905	spo0J	782248..783009 (+)	762	WP_067087518.1	ParB/RepB/Spo0J family partition protein	Regulator
A4H00_RS03910	dnaA	783240..784565 (+)	1326	WP_418080453.1	chromosomal replication initiator protein DnaA	-
A4H00_RS03915	dnaN	784714..785850 (+)	1137	WP_067087522.1	DNA polymerase III subunit beta	-
A4H00_RS03920	-	786184..787092 (+)	909	WP_067087524.1	diacylglycerol/lipid kinase family protein	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 41723.92 Da
• Isoelectric Point: 4.9820

>NTDB_id=177432 A4H00_RS03900 WP_067087516.1 780998..782191(+) (htrA) [Streptococcus marmotae strain HTS5]
MKKSLKFILLFLIGFAGGLAGNLVAPLIHPNKPAQPAVQTKKENEQTTVSNVQYNNENSTTSAVEKVQNAVVSVINYQAT
RENAFSSILGDAARSGELTVAGEGSGVIYKKTDQFAYLVTNTHVIAGAEKIDIQLASGEKVEGELVGSDTYADIAVIKIA
ADKVTAVADFANSDKIKVGETAIAIGSPLGSIYANTVTQGIVSSLSRTVTSKAEDGQTISTNAIQTDTAINPGNSGGPLI
NIQGQVIGITSSKITSSANTGVSVEGMGFAIPANDAVNIINQLEENGKVIRPALGIQMVNLNNLSSEQRKKAGLDNEKVR
AGIVVVSTQKGLPADGQLEQYDVITKIDGDTVETISDLQSALYKHTVGDNISVTYYRAGKEKTIDIKLTHSTEDLSN

Nucleotide

• Length: 1194 bp

>NTDB_id=177432 A4H00_RS03900 WP_067087516.1 780998..782191(+) (htrA) [Streptococcus marmotae strain HTS5]
ATGAAAAAATCACTAAAATTTATCCTTTTATTCTTAATTGGTTTTGCAGGAGGTCTAGCAGGAAACTTAGTTGCCCCTCT
CATTCATCCTAACAAACCTGCCCAACCGGCTGTGCAAACAAAGAAAGAAAATGAACAAACAACTGTCAGTAATGTTCAAT
ATAATAATGAAAATTCGACAACCTCAGCTGTAGAAAAAGTACAAAATGCCGTTGTATCCGTTATTAACTACCAAGCAACA
CGAGAAAATGCGTTTAGTTCGATTTTAGGAGATGCTGCACGTTCTGGAGAATTAACTGTTGCTGGTGAGGGATCTGGGGT
TATCTACAAAAAAACAGATCAATTTGCTTATCTTGTCACGAATACACACGTCATTGCGGGTGCAGAAAAAATTGATATTC
AGCTAGCTTCTGGAGAAAAAGTGGAAGGAGAATTAGTTGGATCTGATACCTATGCAGATATTGCAGTCATAAAAATTGCT
GCTGATAAAGTAACAGCTGTAGCTGATTTTGCTAATTCTGATAAGATTAAGGTTGGTGAAACAGCAATTGCAATTGGTAG
CCCACTTGGAAGTATTTATGCTAATACCGTAACGCAAGGAATTGTTTCCAGTCTCAGCCGAACAGTCACTTCAAAAGCAG
AAGATGGTCAGACAATTTCAACCAACGCTATCCAAACTGATACTGCCATTAACCCTGGTAATTCTGGCGGACCGCTCATT
AATATTCAAGGACAAGTAATTGGAATTACATCCAGCAAAATTACATCAAGTGCCAATACAGGTGTTTCAGTAGAAGGGAT
GGGATTTGCCATTCCAGCAAATGATGCAGTTAATATCATTAATCAGTTAGAAGAAAATGGAAAAGTTATTCGTCCAGCCC
TTGGTATTCAAATGGTAAACTTGAATAACTTATCTAGTGAACAACGGAAAAAAGCTGGGCTTGATAATGAAAAAGTAAGA
GCAGGGATTGTTGTTGTATCCACTCAAAAAGGGTTACCAGCAGATGGACAACTTGAACAATATGACGTGATTACAAAAAT
TGACGGAGATACTGTTGAAACAATCAGTGATTTGCAAAGTGCTCTTTACAAACATACAGTTGGAGATAACATCTCTGTTA
CCTATTACCGTGCAGGAAAAGAAAAAACGATTGACATCAAATTGACACATTCAACAGAAGATTTATCAAACTAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (292-388)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	60.804	100	0.61
htrA	Streptococcus mutans UA159	58.706	100	0.594
htrA	Streptococcus mitis NCTC 12261	58.228	99.496	0.579
htrA	Streptococcus pneumoniae TIGR4	57.576	99.748	0.574
htrA	Streptococcus pneumoniae Rx1	57.576	99.748	0.574
htrA	Streptococcus pneumoniae D39	57.576	99.748	0.574
htrA	Streptococcus pneumoniae R6	57.576	99.748	0.574