Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A4G25_RS12450 Genome accession   NZ_CP015114
Coordinates   2592870..2593586 (-) Length   238 a.a.
NCBI ID   WP_047132795.1    Uniprot ID   A0AB37HAD6
Organism   Staphylococcus condimenti strain DSM 11674     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2587870..2598586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4G25_RS12430 (A4G25_12430) - 2589069..2589713 (+) 645 WP_047132791.1 redox-sensing transcriptional repressor Rex -
  A4G25_RS12435 (A4G25_12435) - 2589761..2589985 (-) 225 WP_047132792.1 sulfurtransferase TusA family protein -
  A4G25_RS12440 (A4G25_12440) - 2590012..2591097 (-) 1086 WP_047132793.1 YeeE/YedE family protein -
  A4G25_RS12445 (A4G25_12445) - 2591307..2592776 (+) 1470 WP_047132794.1 GH32 C-terminal domain-containing protein -
  A4G25_RS12450 (A4G25_12450) agrA 2592870..2593586 (-) 717 WP_047132795.1 quorum-sensing response regulator AgrA Regulator
  A4G25_RS12455 (A4G25_12455) agrC 2593591..2594886 (-) 1296 WP_047132796.1 quorum-sensing sensor histidine kinase AgrC -
  A4G25_RS12460 (A4G25_12460) agrD 2594924..2595061 (-) 138 WP_047132797.1 cyclic lactone autoinducer peptide AgrD -
  A4G25_RS12465 (A4G25_12465) - 2595070..2595645 (-) 576 WP_047132798.1 accessory gene regulator AgrB -
  A4G25_RS13405 (A4G25_12470) - 2596146..2596226 (+) 81 WP_047132799.1 delta-lysin family phenol-soluble modulin -
  A4G25_RS12475 (A4G25_12475) - 2596546..2597346 (-) 801 WP_047132800.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27800.65 Da        Isoelectric Point: 5.0675

>NTDB_id=176779 A4G25_RS12450 WP_047132795.1 2592870..2593586(-) (agrA) [Staphylococcus condimenti strain DSM 11674]
MKIIICEDDQQQRAHIEEIINNYIMIKEKPLEIALSTNDPYEVLEYAKNTNDICCYFLDIQLDADINGIKLGSELRKFDT
VGNIVFVTSHSELTYLTFVYKVAAMDFIFKDDPGEMKSRIIDCIETALTRLQLLSKESNVETIELKRGSNSVYVNYDDVM
FFESSSKSHRLIAHLDNRQIEFYGSLKELSNIDDRFFRCHNSFVINRNNIEEVISKEREIHFKNGEHCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=176779 A4G25_RS12450 WP_047132795.1 2592870..2593586(-) (agrA) [Staphylococcus condimenti strain DSM 11674]
ATGAAAATTATTATTTGTGAAGATGATCAGCAACAACGCGCACATATTGAGGAAATTATTAATAACTACATTATGATTAA
AGAAAAGCCATTAGAAATTGCACTCTCAACTAATGATCCATATGAAGTTCTTGAATATGCTAAAAATACAAATGACATCT
GTTGTTACTTTTTGGATATTCAACTTGACGCAGATATTAATGGGATTAAACTCGGAAGCGAATTACGTAAATTCGATACG
GTTGGAAATATTGTTTTTGTGACAAGTCATAGTGAATTGACTTATTTAACTTTTGTTTATAAAGTAGCTGCGATGGACTT
TATTTTTAAAGATGATCCAGGAGAAATGAAATCACGTATTATCGATTGTATTGAAACAGCGCTTACCCGTTTACAACTAT
TATCTAAAGAAAGCAATGTTGAAACAATCGAATTAAAACGCGGCAGTAATTCTGTATATGTCAATTACGATGACGTCATG
TTTTTCGAATCATCTTCAAAATCTCACAGATTAATTGCACATTTAGACAATCGCCAAATTGAATTTTATGGGAGCTTGAA
AGAACTCAGTAACATTGATGACCGCTTCTTTCGCTGTCACAACAGTTTCGTAATCAACCGCAACAATATCGAAGAAGTGA
TTTCAAAAGAACGGGAAATTCACTTCAAAAATGGTGAACATTGCTATGTCTCTGTTCGTAACCTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794
  comE Streptococcus mitis NCTC 12261

34.263

100

0.361

Multiple sequence alignment