Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A4G25_RS00055 Genome accession   NZ_CP015114
Coordinates   8189..8818 (+) Length   209 a.a.
NCBI ID   WP_047132848.1    Uniprot ID   A0A143PE14
Organism   Staphylococcus condimenti strain DSM 11674     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3189..13818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4G25_RS00030 (A4G25_00030) - 3912..4898 (-) 987 WP_047132843.1 FUSC family protein -
  A4G25_RS00035 (A4G25_00035) map 5146..5913 (+) 768 WP_047132844.1 type I methionyl aminopeptidase -
  A4G25_RS00040 (A4G25_00040) - 6047..6442 (+) 396 WP_047132845.1 hypothetical protein -
  A4G25_RS00045 (A4G25_00045) liaF 6458..7159 (+) 702 WP_047132846.1 cell wall-active antibiotics response protein LiaF -
  A4G25_RS00050 (A4G25_00050) vraS 7156..8199 (+) 1044 WP_047132847.1 sensor histidine kinase Regulator
  A4G25_RS00055 (A4G25_00055) vraR 8189..8818 (+) 630 WP_047132848.1 response regulator transcription factor Regulator
  A4G25_RS00060 (A4G25_00060) - 8867..9445 (-) 579 WP_047132849.1 beta-class carbonic anhydrase -
  A4G25_RS00065 (A4G25_00065) - 9647..10723 (-) 1077 WP_047132850.1 YihY/virulence factor BrkB family protein -
  A4G25_RS00070 (A4G25_00070) - 10843..11139 (-) 297 WP_047132851.1 hypothetical protein -
  A4G25_RS00075 (A4G25_00075) - 11147..11611 (-) 465 WP_047132852.1 low molecular weight protein-tyrosine-phosphatase -
  A4G25_RS00080 (A4G25_00080) - 11846..12052 (+) 207 WP_047132853.1 DUF1128 family protein -
  A4G25_RS00085 (A4G25_00085) - 12091..13329 (+) 1239 WP_047132854.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23736.22 Da        Isoelectric Point: 4.6397

>NTDB_id=176752 A4G25_RS00055 WP_047132848.1 8189..8818(+) (vraR) [Staphylococcus condimenti strain DSM 11674]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELHPDLILMDLLMEDMDGVEATQQIKKDLPDIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTQHNESVFEAEVLVKMRNRMNQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=176752 A4G25_RS00055 WP_047132848.1 8189..8818(+) (vraR) [Staphylococcus condimenti strain DSM 11674]
ATGACGATTAAAGTGCTATTTGTTGATGACCATGAAATGGTGCGTATCGGCATTTCAAGTTATTTATCGACACAACCAGA
TATTGAAGTGGTAGGGGAAGGAAAGTCTGGAAAAGAAGCTATTGAAAAAGCACATGAACTGCATCCTGATTTAATATTAA
TGGATTTATTGATGGAAGATATGGATGGTGTTGAAGCTACACAGCAAATCAAAAAAGATTTGCCAGATATTAAAGTGTTG
ATGTTAACAAGTTATATTGAAGATAATGAAGTTTATCGTGCACTAGATGCAGGGGTAGACAGTTATATCCTCAAAACAAC
AAGTGCAAGTGACATTGCAGAGGCAATTAGAAAAACACAACATAATGAATCTGTATTTGAAGCAGAAGTACTTGTTAAAA
TGCGTAATCGCATGAACCAACGTGCTGAATTATATGAAATGCTCACTGAAAGAGAGATGGAAATCCTGTTATTAATTGCA
AAAGGGTATTCCAATCAAGAAATTGCAAGTGCTTCTCATATTACAATTAAGACAGTAAAAACGCATGTTAGTAATATTTT
AAGTAAATTAGAAGTGCAAGATAGAACACAAGCAGTTATTTACGCTTTCCAACATGATTTAATCCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A143PE14

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

91.388

100

0.914
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment