Detailed information NTG0176751

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A4G25_RS00050
• Genome accession: NZ_CP015114
• Coordinates: 7156..8199 (+)
• Length: 347 a.a.
• NCBI ID: WP_047132847.1
• Uniprot ID: A0A143P7E7
• Organism: Staphylococcus condimenti strain DSM 11674
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2156..13199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4G25_RS00025 (A4G25_00025)	-	3137..3862 (+)	726	WP_047132842.1	type 1 glutamine amidotransferase	-
A4G25_RS00030 (A4G25_00030)	-	3912..4898 (-)	987	WP_047132843.1	FUSC family protein	-
A4G25_RS00035 (A4G25_00035)	map	5146..5913 (+)	768	WP_047132844.1	type I methionyl aminopeptidase	-
A4G25_RS00040 (A4G25_00040)	-	6047..6442 (+)	396	WP_047132845.1	hypothetical protein	-
A4G25_RS00045 (A4G25_00045)	liaF	6458..7159 (+)	702	WP_047132846.1	cell wall-active antibiotics response protein LiaF	-
A4G25_RS00050 (A4G25_00050)	vraS	7156..8199 (+)	1044	WP_047132847.1	sensor histidine kinase	Regulator
A4G25_RS00055 (A4G25_00055)	vraR	8189..8818 (+)	630	WP_047132848.1	response regulator transcription factor	Regulator
A4G25_RS00060 (A4G25_00060)	-	8867..9445 (-)	579	WP_047132849.1	beta-class carbonic anhydrase	-
A4G25_RS00065 (A4G25_00065)	-	9647..10723 (-)	1077	WP_047132850.1	YihY/virulence factor BrkB family protein	-
A4G25_RS00070 (A4G25_00070)	-	10843..11139 (-)	297	WP_047132851.1	hypothetical protein	-
A4G25_RS00075 (A4G25_00075)	-	11147..11611 (-)	465	WP_047132852.1	low molecular weight protein-tyrosine-phosphatase	-
A4G25_RS00080 (A4G25_00080)	-	11846..12052 (+)	207	WP_047132853.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.54 Da
• Isoelectric Point: 5.0629

>NTDB_id=176751 A4G25_RS00050 WP_047132847.1 7156..8199(+) (vraS) [Staphylococcus condimenti strain DSM 11674]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIVFFQGMFYTQIFGIPVFLFLNIIVILMCIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQNIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=176751 A4G25_RS00050 WP_047132847.1 7156..8199(+) (vraS) [Staphylococcus condimenti strain DSM 11674]
ATGAACCATTATATAAGAGCGATAGGTTCAATGTTAATATTGATTTACAGCATTTTAGCTATTTTCTTTTTCATCGATAA
AGTCTTTGTAAATATTGTCTTTTTTCAAGGAATGTTCTATACACAAATTTTCGGAATTCCAGTTTTTTTGTTTTTAAATA
TCATTGTAATATTGATGTGTATTATCGTAGGTTCTGTATTAGCGTATAAAGTGAACCAGCAAAATCATTGGATTAAAGAC
CAAATTGAACATTCTATTGAAGGTGAAGTCGTAGGTATTAATGATCAAAATATCGAACTTTATCAAGAGACGTTAGATAT
CTATCATATGTTGGTACCTTTAAATCAAGAATTGCACCGCTTACGTATTAAAACACAAGATTTAACGAATGAAACTTATA
ATTTAAATGATACAAAAGTAAAAAAAATTATAGAAGATGAACGTCAACGTTTAGCAAGAGAACTGCATGACTCGGTGAGC
CAGCAATTATTTGCTGCAAGTATGATGTTGTCTGCTATAAAGGAAACTAAGTTAGAACCGCCTTTAGATCAACAAATTCC
AACACTTGAAAAGATGGTACAAGATTCACAACTTGAAATGCGTGCTTTATTGCTTCATTTACGTCCATTAGGCTTAAAGG
ACCGTTCATTAGGTGAAGGTATTAAAGACTTGGTTGTAGACTTGCAGAAAAAAGTTCCGATGAAGGTAGTTTATGATATC
GAAGATTTTGAAGTGCCAAAAGGGATAGAAGATCATTTATTCCGAATAACACAAGAAGGTATATCAAACACTTTGCGACA
TGCCGAAGGTACTAAATTGACGATAGATTTATATAATAAAGACGATTATTTACTATTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A143P7E7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	85.591	100	0.856