Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   BTR42_RS11040 Genome accession   NZ_CP018822
Coordinates   2217686..2218996 (-) Length   436 a.a.
NCBI ID   WP_058621373.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus DSM 16831     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2212686..2223996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTR42_RS11000 (BTR42_10740) - 2213071..2213271 (-) 201 WP_077497723.1 bacteriocin -
  BTR42_RS11005 (BTR42_10745) comD/comD3 2213404..2214768 (-) 1365 WP_077497726.1 sensor histidine kinase Regulator
  BTR42_RS11010 (BTR42_10750) comE/comE2 2214781..2215509 (-) 729 WP_012962512.1 LytR/AlgR family response regulator transcription factor Regulator
  BTR42_RS11015 (BTR42_10755) - 2215608..2215901 (-) 294 WP_009854994.1 bacteriocin immunity protein -
  BTR42_RS11020 (BTR42_10760) - 2215952..2216104 (-) 153 WP_231873055.1 hypothetical protein -
  BTR42_RS11025 (BTR42_10765) - 2216448..2216759 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  BTR42_RS11030 (BTR42_10770) - 2216771..2216920 (-) 150 WP_013643483.1 hypothetical protein -
  BTR42_RS11035 (BTR42_10775) - 2216977..2217228 (-) 252 WP_231844599.1 DUF3884 family protein -
  BTR42_RS12705 (BTR42_10780) comC/comC1 2217529..2217669 (+) 141 WP_014295304.1 hypothetical protein Regulator
  BTR42_RS11040 (BTR42_10785) comD/comD1 2217686..2218996 (-) 1311 WP_058621373.1 sensor histidine kinase Regulator
  BTR42_RS11045 (BTR42_10790) comE/comE1 2219001..2219732 (-) 732 WP_077497729.1 response regulator transcription factor Regulator
  BTR42_RS11050 (BTR42_10795) - 2219749..2220075 (-) 327 WP_009855002.1 LytTR family DNA-binding domain-containing protein -
  BTR42_RS11055 (BTR42_10800) - 2220259..2221551 (-) 1293 WP_013643489.1 glycosyltransferase family 2 protein -
  BTR42_RS11060 (BTR42_10805) - 2221553..2221852 (-) 300 WP_013643490.1 DUF3884 family protein -
  BTR42_RS11065 (BTR42_10810) - 2221878..2222060 (-) 183 WP_013643491.1 hypothetical protein -
  BTR42_RS11070 (BTR42_10815) - 2222142..2222351 (-) 210 WP_013643492.1 helix-turn-helix domain-containing protein -
  BTR42_RS11075 (BTR42_10820) - 2222341..2223354 (-) 1014 WP_077497732.1 bacteriocin biosynthesis protein -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 50940.86 Da        Isoelectric Point: 5.6978

>NTDB_id=176239 BTR42_RS11040 WP_058621373.1 2217686..2218996(-) (comD/comD1) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MLDYLFLCLIVNSFILYIYSQVRGEKLNFFEILIAVAVFVWVDHAWFYFIICNFIILILLSYLKNRSLPLTLHVFYGVFP
WIVESVFRRLIGFFMLPIIGLNYLNVGENNIIFMCVELTSLMLYILLVKISKFDFQRFIEMVSVSILRFFLIVTDVTMIA
FYVAIEFLTGMEVYGGVPNLVYRQWLVALYFTFFILMLFYMNRSYQNWLEKEVSLAREQELHSLSVYSKQIEGLYEELRA
FRHDYANILVSLKEGIDQNDMDMVRNIYNSVLEESGHLVQNKKFDIGRLINIDNDAIKSVLSAKFLEAESYHIAVQLEVK
DKIGLPEIPLLDYVRLLSILCDNAIEAAMEAENPAMIIACFYQGDDYLLVIDNTTKEERVPVELIYQKNYSSKGFGRGVG
LKTVNQMLKKYPNMSVQTSSKNYHFRQTICIKKSFD

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=176239 BTR42_RS11040 WP_058621373.1 2217686..2218996(-) (comD/comD1) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
ATGTTGGATTACTTATTTCTTTGCTTAATAGTAAATTCGTTTATTCTATACATTTATTCTCAAGTCAGAGGTGAGAAGTT
AAACTTTTTTGAGATATTAATAGCAGTTGCTGTTTTTGTATGGGTTGATCATGCTTGGTTTTATTTTATTATATGTAATT
TTATTATTCTGATATTGTTATCTTATCTAAAAAATAGGTCTTTACCACTAACACTTCATGTCTTTTATGGTGTTTTTCCT
TGGATTGTTGAGAGTGTTTTTAGGCGTTTGATAGGTTTCTTTATGCTTCCAATCATTGGTTTAAATTATCTGAATGTAGG
TGAAAATAATATAATTTTTATGTGTGTCGAGCTAACATCCCTAATGCTTTATATTTTGCTAGTGAAAATTTCTAAATTTG
ATTTTCAAAGATTTATAGAAATGGTTAGTGTCAGCATATTAAGATTTTTTCTTATTGTTACTGATGTAACGATGATTGCT
TTTTATGTGGCTATTGAATTTCTAACAGGTATGGAAGTTTATGGTGGTGTCCCAAACTTGGTTTATCGCCAATGGTTGGT
GGCTCTCTATTTCACTTTCTTCATTTTAATGCTGTTTTATATGAATCGCTCTTATCAAAATTGGCTTGAGAAAGAAGTAT
CATTAGCGCGAGAACAAGAACTGCATTCTTTGTCGGTATATAGCAAGCAAATCGAAGGCTTATATGAAGAACTAAGAGCT
TTTCGTCATGATTATGCCAATATTTTAGTGAGTTTAAAAGAAGGAATCGACCAAAATGATATGGATATGGTCAGAAATAT
TTACAATTCTGTATTAGAAGAGTCAGGGCACCTTGTTCAGAATAAAAAATTTGATATTGGACGATTGATTAATATTGACA
ATGATGCAATAAAAAGTGTATTATCAGCAAAGTTTTTAGAGGCTGAGTCTTATCACATTGCCGTTCAATTAGAGGTTAAA
GATAAGATCGGACTTCCTGAGATACCATTACTAGACTATGTGCGACTTTTGTCGATTTTGTGTGATAATGCGATTGAAGC
AGCTATGGAAGCTGAAAATCCTGCCATGATTATTGCTTGTTTCTATCAAGGGGATGACTATTTACTAGTTATCGATAACA
CTACAAAAGAAGAACGAGTTCCTGTGGAATTGATTTATCAGAAGAATTATTCAAGTAAGGGCTTTGGACGAGGTGTTGGT
CTTAAAACGGTTAACCAGATGTTGAAAAAGTATCCAAATATGTCGGTACAAACATCAAGTAAAAATTATCATTTCAGACA
AACAATATGTATAAAAAAATCATTCGACTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(331-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

75

53.211

0.399