Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   BSL41_RS10365 Genome accession   NZ_CP018347
Coordinates   1882571..1883248 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain SWU02     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1877571..1888248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSL41_RS10335 - 1877734..1878363 (-) 630 WP_000762091.1 NAD(P)-dependent oxidoreductase -
  BSL41_RS10340 - 1878601..1878801 (+) 201 WP_001814296.1 hypothetical protein -
  BSL41_RS10345 - 1879231..1879371 (+) 141 WP_000422775.1 MazG-like protein -
  BSL41_RS10350 - 1879378..1879554 (+) 177 WP_000166031.1 MazG-like protein -
  BSL41_RS10355 thrS 1879612..1881555 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  BSL41_RS10360 - 1881604..1882578 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  BSL41_RS10365 braR 1882571..1883248 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  BSL41_RS10370 - 1883404..1884477 (+) 1074 WP_001273823.1 DUF2974 domain-containing protein -
  BSL41_RS10375 - 1884568..1884870 (-) 303 WP_000281609.1 hypothetical protein -
  BSL41_RS10380 - 1884938..1885375 (-) 438 WP_001166785.1 Rrf2 family transcriptional regulator -
  BSL41_RS10385 - 1885451..1886293 (-) 843 WP_000160938.1 metallophosphoesterase -
  BSL41_RS10390 - 1886405..1887055 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  BSL41_RS12775 - 1887036..1887227 (+) 192 WP_001816503.1 hypothetical protein -
  BSL41_RS10400 - 1887253..1887928 (+) 676 Protein_1872 nicotinamide mononucleotide transporter -
  BSL41_RS12870 - 1888030..1888101 (+) 72 Protein_1873 glutamine ABC transporter permease -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=175166 BSL41_RS10365 WP_000548959.1 1882571..1883248(-) (braR) [Streptococcus pneumoniae strain SWU02]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=175166 BSL41_RS10365 WP_000548959.1 1882571..1883248(-) (braR) [Streptococcus pneumoniae strain SWU02]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369