Detailed information NTG0174444

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A1140_RS07300
• Genome accession: NZ_CP014834
• Coordinates: 1502838..1503881 (-)
• Length: 347 a.a.
• NCBI ID: WP_103207603.1
• Uniprot ID: A0A2K3ZIM8
• Organism: Staphylococcus felis strain BN1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1497838..1508881

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A1140_RS07270 (A1140_07130)	-	1498846..1499031 (-)	186	WP_103207656.1	DUF1128 family protein	-
A1140_RS07275 (A1140_07135)	-	1499190..1499654 (+)	465	WP_103207612.1	low molecular weight protein-tyrosine-phosphatase	-
A1140_RS07280 (A1140_07140)	-	1499656..1499943 (+)	288	WP_103207611.1	YtxH domain-containing protein	-
A1140_RS07285 (A1140_07145)	-	1500306..1501529 (+)	1224	WP_103207609.1	YihY/virulence factor BrkB family protein	-
A1140_RS07290 (A1140_07150)	-	1501560..1502132 (+)	573	WP_103207607.1	carbonic anhydrase	-
A1140_RS07295 (A1140_07155)	vraR	1502219..1502848 (-)	630	WP_103207605.1	response regulator transcription factor	Regulator
A1140_RS07300 (A1140_07160)	vraS	1502838..1503881 (-)	1044	WP_103207603.1	sensor histidine kinase	Regulator
A1140_RS07305 (A1140_07165)	liaF	1503878..1504579 (-)	702	WP_103207601.1	cell wall-active antibiotics response protein LiaF	-
A1140_RS07310 (A1140_07170)	-	1504592..1504981 (-)	390	WP_349420707.1	hypothetical protein	-
A1140_RS07315 (A1140_07175)	map	1505076..1505837 (-)	762	WP_115856682.1	type I methionyl aminopeptidase	-
A1140_RS07320 (A1140_07180)	-	1505928..1506932 (+)	1005	WP_181894655.1	aromatic acid exporter family protein	-
A1140_RS07325 (A1140_07185)	-	1507012..1507737 (-)	726	WP_115871432.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40184.49 Da
• Isoelectric Point: 5.1680

>NTDB_id=174444 A1140_RS07300 WP_103207603.1 1502838..1503881(-) (vraS) [Staphylococcus felis strain BN1]
MNHYVRTIGSMLILVYSMFTAFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLIVIFLCIIVGSVIAYKINQQNDWLQQ
QIERAFEGETVGVNDQQLELYNETLEIYRSLVPLNQELHKMRIKTQNLTNESYNLNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETNLNPPLDQQIPTLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIRSLVTELQKKVPMKVIQEI
DEFDVPKGIEDHLFRITQEAISNTLRHAKGEQVTVELLKREDYLLLRIQDDGIGFNVDDKIEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEESHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=174444 A1140_RS07300 WP_103207603.1 1502838..1503881(-) (vraS) [Staphylococcus felis strain BN1]
ATGAATCACTATGTCAGAACGATTGGGTCAATGCTCATACTAGTTTACAGTATGTTTACAGCTTTCTTTTTTATCGATAA
AGTTTTTGTGAATATCATATTTTTTCAAGGTATGTTTTACACTCAAATCTTCGGTATTCCTGTATTTTTATTTCTTAACT
TAATTGTCATTTTTTTGTGTATTATTGTGGGTAGTGTAATAGCGTATAAGATTAATCAACAAAATGATTGGTTACAACAA
CAGATTGAGCGTGCATTTGAAGGTGAAACAGTCGGTGTTAACGATCAGCAACTAGAGCTGTATAATGAAACATTAGAGAT
TTACCGTTCATTAGTACCGCTCAATCAAGAATTACATAAAATGCGAATTAAAACTCAAAATTTGACAAATGAATCTTACA
ACTTAAATGATATAAAAGTAAAAAAAATAATTGAAGATGAACGTCAACGGTTAGCTAGAGAGCTTCACGATAGTGTTTCG
CAGCAATTGTTTGCAGCTAGTATGATGTTATCAGCTATTAAAGAAACAAACTTAAATCCACCACTTGATCAACAGATACC
AACACTTGAAAAAATGATTCAAGACTCACAACTTGAAATGAGAGCATTATTATTACACTTACGTCCAATAGGTTTGAAGG
ATAAATCATTAGGTGAAGGCATACGATCGTTAGTGACTGAATTACAAAAGAAAGTACCTATGAAAGTTATACAAGAAATT
GATGAGTTTGATGTTCCAAAGGGTATAGAAGATCACTTATTTAGAATCACACAAGAGGCAATCTCCAATACGTTACGTCA
TGCTAAGGGTGAACAAGTGACGGTTGAATTGTTAAAAAGAGAAGACTATTTATTATTGCGTATTCAAGATGATGGTATCG
GCTTTAATGTGGACGATAAAATTGAACAAAGTTATGGTTTGAAAAATATGCGTGAAAGAGCAATTGAAATTGGTGCAACT
TTTCATATCGTCTCTTTGCCTGATGCAGGAACACGTATCGAGGTTAAAGCACCATTAGAAAAGGAGGAAAGTCATGACAA
TTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2K3ZIM8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	82.997	100	0.83