Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CKU_RS12835 Genome accession   NZ_CP014791
Coordinates   2563714..2564379 (-) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain MCRF184     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2558714..2569379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKU_RS12810 (CKU_2374) - 2559168..2559281 (-) 114 WP_072468803.1 hypothetical protein -
  CKU_RS12820 (CKU_2375) - 2559956..2561956 (-) 2001 WP_000776737.1 ABC transporter permease -
  CKU_RS12825 (CKU_2376) - 2561953..2562708 (-) 756 WP_000923765.1 ABC transporter ATP-binding protein -
  CKU_RS12830 (CKU_2377) braS 2562816..2563703 (-) 888 WP_000143415.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  CKU_RS12835 (CKU_2378) braR 2563714..2564379 (-) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  CKU_RS12840 (CKU_2379) - 2564405..2564605 (-) 201 WP_000604722.1 hypothetical protein -
  CKU_RS12850 (CKU_2380) - 2564803..2566227 (+) 1425 WP_000953745.1 alkaline phosphatase -
  CKU_RS14115 (CKU_2381) - 2566264..2566365 (-) 102 WP_000731972.1 SE2200 family small protein -
  CKU_RS12855 (CKU_2382) - 2566487..2566942 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  CKU_RS12860 (CKU_2383) - 2567182..2567943 (-) 762 WP_000323450.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=174143 CKU_RS12835 WP_000697883.1 2563714..2564379(-) (braR) [Staphylococcus aureus strain MCRF184]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=174143 CKU_RS12835 WP_000697883.1 2563714..2564379(-) (braR) [Staphylococcus aureus strain MCRF184]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGTCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment